Immunogenicity 5386

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
UCHL1
Transcript ID
NM_004181
HLA INFO
DQA*01:03 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*06:02
sequence
Full length protein sequence (223 aa)
MQLKP
1
MEINP
6
EMLNK
11
VLSRL
16
GVAGQ
21
WRFVD
26
VLGLE
31
EESLG
36
SVPAP
41
ACALL
46
LLFPL
51
TAQHE
56
NFRKK
61
QIEEL
66
KGQEV
71
SPKVY
76
FMKQT
81
IGNSC
86
GTIGL
91
IHAVA
96
NNQDK
101
LGFED
106
GSVLK
111
QFLSE
116
TEKMS
121
PEDRA
126
KCFEK
131
NEAIQ
136
AAHDA
141
VAQEG
146
QCRVD
151
DKVNF
156
HFILF
161
NNVDG
166
HLYEL
171
DGRMP
176
FPVNH
181
GASSE
186
DTLLK
191
DAAKV
196
CREFT
201
EREQG
206
EVRFS
211
AVALC
216
KAA
221
Mutation Information
DNA mutation:
None
Peptide Range:
6 ~ 30
Mut AA position:
18 (13 in Wild Type peptide)
Alignment
Wild Type:
"MEINPEMLNKVLSRLGVAGQWRFVD
||||||||||||.||||||||||||
Mutant:
MEINPEMLNKVLYRLGVAGQWRFVD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) UCHL1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay