Immunogenicity 5402

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FAM49B
Transcript ID
NM_001256763
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (324 aa)
MGNLL
1
KVLTC
6
TDLEQ
11
GPNFF
16
LDFEN
21
AQPTE
26
SEKEI
31
YNQVN
36
VVLKD
41
AEGIL
46
EDLQS
51
YRGAG
56
HEIRE
61
AIQHP
66
ADEKL
71
QEKAW
76
GAVVP
81
LVGKL
86
KKFYE
91
FSQRL
96
EAALR
101
GLLGA
106
LTSTP
111
YSPTQ
116
HLERE
121
QALAK
126
QFAEI
131
LHFTL
136
RFDEL
141
KMTNP
146
AIQND
151
FSYYR
156
RTLSR
161
MRINN
166
VPAEG
171
ENEVN
176
NELAN
181
RMSLF
186
YAEAT
191
PMLKT
196
LSDAT
201
TKFVS
206
ENKNL
211
PIENT
216
TDCLS
221
TMASV
226
CRVML
231
ETPEY
236
RSRFT
241
NEETV
246
SFCLR
251
VMVGV
256
IILYD
261
HVHPV
266
GAFAK
271
TSKID
276
MKGCI
281
KVLKD
286
QPPNS
291
VEGLL
296
NALRY
301
TTKHL
306
NDETT
311
SKQIK
316
SMLQ
321
Mutation Information
DNA mutation:
None
Peptide Range:
228 ~ 252
Mut AA position:
240 (13 in Wild Type peptide)
Alignment
Wild Type:
"ASVCRVMLETPEYRSRFTNEETVSF
||||||||||||.||||||||||||
Mutant:
ASVCRVMLETPECRSRFTNEETVSF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FAM49B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay