Immunogenicity 5452

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ICOSLG
Transcript ID
NM_015259
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (302 aa)
MRLGS
1
PGLLF
6
LLFSS
11
LRADT
16
QEKEV
21
RAMVG
26
SDVEL
31
SCACP
36
EGSRF
41
DLNDV
46
YVYWQ
51
TSESK
56
TVVTY
61
HIPQN
66
SSLEN
71
VDSRY
76
RNRAL
81
MSPAG
86
MLRGD
91
FSLRL
96
FNVTP
101
QDEQK
106
FHCLV
111
LSQSL
116
GFQEV
121
LSVEV
126
TLHVA
131
ANFSV
136
PVVSA
141
PHSPS
146
QDELT
151
FTCTS
156
INGYP
161
RPNVY
166
WINKT
171
DNSLL
176
DQALQ
181
NDTVF
186
LNMRG
191
LYDVV
196
SVLRI
201
ARTPS
206
VNIGC
211
CIENV
216
LLQQN
221
LTVGS
226
QTGND
231
IGERD
236
KITEN
241
PVSTG
246
EKNAA
251
TWSIL
256
AVLCL
261
LVVVA
266
VAIGW
271
VCRDR
276
CLQHS
281
YAGAW
286
AVSPE
291
TELTG
296
HV
301
Mutation Information
DNA mutation:
None
Peptide Range:
282 ~ 302
Mut AA position:
294 (13 in Wild Type peptide)
Alignment
Wild Type:
"LQHSYAGAWAVSPETELTGHV
||||||||||||.||||||||
Mutant:
LQHSYAGAWAVSSETELTGHV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ICOSLG

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay