Immunogenicity 5455

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HSPH1
Transcript ID
NM_006644
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (858 aa)
MSVVG
1
LDVGS
6
QSCYI
11
AVARA
16
GGIET
21
IANEF
26
SDRCT
31
PSVIS
36
FGSKN
41
RTIGV
46
AAKNQ
51
QITHA
56
NNTVS
61
NFKRF
66
HGRAF
71
NDPFI
76
QKEKE
81
NLSYD
86
LVPLK
91
NGGVG
96
IKVMY
101
MGEEH
106
LFSVE
111
QITAM
116
LLTKL
121
KETAE
126
NSLKK
131
PVTDC
136
VISVP
141
SFFTD
146
AERRS
151
VLDAA
156
QIVGL
161
NCLRL
166
MNDMT
171
AVALN
176
YGIYK
181
QDLPS
186
LDEKP
191
RIVVF
196
VDMGH
201
SAFQV
206
SACAF
211
NKGKL
216
KVLGT
221
AFDPF
226
LGGKN
231
FDEKL
236
VEHFC
241
AEFKT
246
KYKLD
251
AKSKI
256
RALLR
261
LYQEC
266
EKLKK
271
LMSSN
276
STDLP
281
LNIEC
286
FMNDK
291
DVSGK
296
MNRSQ
301
FEELC
306
AELLQ
311
KIEVP
316
LYSLL
321
EQTHL
326
KVEDV
331
SAVEI
336
VGGAT
341
RIPAV
346
KERIA
351
KFFGK
356
DISTT
361
LNADE
366
AVARG
371
CALQC
376
AILSP
381
AFKVR
386
EFSVT
391
DAVPF
396
PISLI
401
WNHDS
406
EDTEG
411
VHEVF
416
SRNHA
421
APFSK
426
VLTFL
431
RRGPF
436
ELEAF
441
YSDPQ
446
GVPYP
451
EAKIG
456
RFVVQ
461
NVSAQ
466
KDGEK
471
SRVKV
476
KVRVN
481
THGIF
486
TISTA
491
SMVEK
496
VPTEE
501
NEMSS
506
EADME
511
CLNQR
516
PPENP
521
DTDKN
526
VQQDN
531
SEAGT
536
QPQVQ
541
TDAQQ
546
TSQSP
551
PSPEL
556
TSEEN
561
KIPDA
566
DKANE
571
KKVDQ
576
PPEAK
581
KPKIK
586
VVNVE
591
LPIEA
596
NLVWQ
601
LGKDL
606
LNMYI
611
ETEGK
616
MIMQD
621
KLEKE
626
RNDAK
631
NAVEE
636
YVYEF
641
RDKLC
646
GPYEK
651
FICEQ
656
DHQNF
661
LRLLT
666
ETEDW
671
LYEEG
676
EDQAK
681
QAYVD
686
KLEEL
691
MKIGT
696
PVKVR
701
FQEAE
706
ERPKM
711
FEELG
716
QRLQH
721
YAKIA
726
ADFRN
731
KDEKY
736
NHIDE
741
SEMKK
746
VEKSV
751
NEVME
756
WMNNV
761
MNAQA
766
KKSLD
771
QDPVV
776
RAQEI
781
KTKIK
786
ELNNT
791
CEPVV
796
TQPKP
801
KIESP
806
KLERT
811
PNGPN
816
IDKKE
821
EDLED
826
KNNFG
831
AEPPH
836
QNGEC
841
YPNEK
846
NSVNM
851
DLD
856
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 19
Mut AA position:
7 (7 in Wild Type peptide)
Alignment
Wild Type:
"MSVVGLDVGSQSCYIAVARAGGIET
||||||.||||||||||||
Mutant:
MSVVGLHVGSQSCYIAVAR------"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HSPH1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay