Immunogenicity 5484
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SLFN12
Transcript ID
NM_018042
HLA INFO
C*06:02
TCR INFO
No TCR info found!
Full length protein sequence (578 aa)
MNISV
1
DLETN
6
YAELV
11
LDVGR
16
VTLGE
21
NSRKK
26
MKDCK
31
LRKKQ
36
NESVS
41
RAMCA
46
LLNSG
51
GGVIK
56
AEIEN
61
EDYSY
66
TKDGI
71
GLDLE
76
NSFSN
81
ILLFV
86
PEYLD
91
FMQNG
96
NYFLI
101
FVKSW
106
SLNTS
111
GLRIT
116
TLSSN
121
LYKRD
126
ITSAK
131
VMNAT
136
AALEF
141
LKDMK
146
KTRGR
151
LYLRP
156
ELLAK
161
RPCVD
166
IQEEN
171
NMKAL
176
AGVFF
181
DRTEL
186
DRKEK
191
LTFTE
196
STHVE
201
IKNFS
206
TEKLL
211
QRIKE
216
ILPQY
221
VSAFA
226
NTDGG
231
YLFIG
236
LNEDK
241
EIIGF
246
KAEMS
251
DLDDL
256
EREIE
261
KSIRK
266
MPVHH
271
FCMEK
276
KKINY
281
SCKFL
286
GVYDK
291
GSLCG
296
YVCAL
301
RVERF
306
CCAVF
311
AKEPD
316
SWHVK
321
DNRVM
326
QLTRK
331
EWIQF
336
MVEAE
341
PKFSS
346
SYEEV
351
ISQIN
356
TSLPA
361
PHSWP
366
LLEWQ
371
RQRHH
376
CPGLS
381
GRITY
386
TPENL
391
CRKLF
396
LQHEG
401
LKQLI
406
CEEMD
411
SVRKG
416
SLIFS
421
RSWSV
426
DLGLQ
431
ENHKV
436
LCDAL
441
LISQD
446
SPPVL
451
YTFHM
456
VQDEE
461
FKGYS
466
TQTAL
471
TLKQK
476
LAKIG
481
GYTKK
486
VCVMT
491
KIFYL
496
SPEGM
501
TSCQY
506
DLRSQ
511
VIYPE
516
SYYFT
521
RRKYL
526
LKALF
531
KALKR
536
LKSLR
541
DQFSF
546
AENLY
551
QIIGI
556
DCFQK
561
NDKKM
566
FKSCR
571
RLT
576
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 21
Mut AA position:
9 (9 in Wild Type peptide)
Alignment
Wild Type:
"MNISVDLETNYAELVLDVGRVTLGE
||||||||.||||||||||||
Mutant:
MNISVDLEMNYAELVLDVGRV----"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) SLFN12
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay