Immunogenicity 5498
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LOXHD1
Transcript ID
NM_144612
HLA INFO
C*08:02
TCR INFO
No TCR info found!
Full length protein sequence (2211 aa)
MMPQK
1
KRRRK
6
KDIDF
11
LALYE
16
AELLN
21
YASED
26
DEGEL
31
EHEYY
36
KARVY
41
EVVTA
46
TGDVR
51
GAGTD
56
ANVFI
61
TLFGE
66
NGLSP
71
KLQLT
76
SKSKS
81
AFEKG
86
NVDVF
91
RVRTN
96
NVGLI
101
YKVRI
106
EHDNT
111
GLNAS
116
WYLDH
121
VIVTD
126
MKRPH
131
LRYYF
136
NCNNW
141
LSKVE
146
GDRQW
151
CRDLL
156
ASFNP
161
MDMPR
166
GNKYE
171
VKVYT
176
GDVIG
181
AGTDA
186
DVFIN
191
IFGEY
196
GDTGE
201
RRLEN
206
EKDNF
211
EKGAE
216
DRFIL
221
DAPDL
226
GQLMK
231
INVGH
236
NNKGG
241
SAGWF
246
LSQIV
251
IEDIG
256
NKRKY
261
DFPLN
266
RWLAL
271
DEDDG
276
KIQRD
281
ILVGG
286
AETTA
291
ITYIV
296
TVFTG
301
DVRGA
306
GTKSK
311
IYLVM
316
YGARG
321
NKNSG
326
KIFLE
331
GGVFD
336
RGRTD
341
IFHIE
346
LAVLL
351
SPLSR
356
VSVGH
361
GNVGV
366
NRGWF
371
CEKVV
376
ILCPF
381
TGIQQ
386
TFPCS
391
NWLDE
396
KKADG
401
LIERQ
406
LYEMV
411
SLRKK
416
RLKKF
421
PWSLW
426
VWTTD
431
LKKAG
436
TNSPI
441
FIQIY
446
GQKGR
451
TDEIL
456
LNPNN
461
KWFKP
466
GIIEK
471
FRIEL
476
PDLGR
481
FYKIR
486
VWHDK
491
RSSGS
496
GWHLE
501
RMTLM
506
NTLNK
511
DKYNF
516
NCNRW
521
LDANE
526
DDNEI
531
VREMT
536
AEGPT
541
VRRIM
546
GMARY
551
HVTVC
556
TGELE
561
GAGTD
566
ANVYL
571
CLFGD
576
VGDTG
581
ERLLY
586
NCRNN
591
TDLFE
596
KGNAD
601
EFTIE
606
SVTMR
611
NVRRV
616
RIRHD
621
GKGSG
626
SGWYL
631
DRVLV
636
REEGQ
641
PESDN
646
VEFPC
651
LRWLD
656
KDKDD
661
GQLVR
666
ELLPS
671
DSSAT
676
LKNFR
681
YHISL
686
KTGDV
691
SGAST
696
DSRVY
701
IKLYG
706
DKSDT
711
IKQVL
716
LVSDN
721
NLKDY
726
FERGR
731
VDEFT
736
LETLN
741
IGNIN
746
RLVIG
751
HDSTG
756
MHASW
761
FLGSV
766
QIRVP
771
RQGKQ
776
YTFPA
781
NRWLD
786
KNQAD
791
GRLEV
796
ELYPS
801
EVVEI
806
QKLVH
811
YEVEI
816
WTGDV
821
GGAGT
826
SARVY
831
MQIYG
836
EKGKT
841
EVLFL
846
SSRSK
851
VFERA
856
SKDTF
861
QLEAA
866
DVGEV
871
YKLRL
876
GHTGE
881
GFGPS
886
WFVDT
891
VWLRH
896
LVVRE
901
VDLTP
906
EEEAR
911
KKKEK
916
DKLRQ
921
LLKKE
926
RLKAK
931
LQRKK
936
KKRKG
941
SDEED
946
EGEEE
951
ESSSS
956
EESSS
961
EEEEM
966
EEEEE
971
EEEFG
976
PGMQE
981
VIEQH
986
KFEAH
991
RWLAR
996
GKEDN
1001
ELVVE
1006
LVPAG
1011
KPGPE
1016
RNTYE
1021
VQVVT
1026
GNVPK
1031
AGTDA
1036
NVYLT
1041
IYGEE
1046
YGDTG
1051
ERPLK
1056
KSDKS
1061
NKFEQ
1066
GQTDT
1071
FTIYA
1076
IDLGA
1081
LTKIR
1086
IRHDN
1091
TGNRA
1096
GWFLD
1101
RIDIT
1106
DMNNE
1111
ITYYF
1116
PCQRW
1121
LAVEE
1126
DDGQL
1131
SRELL
1136
PVDES
1141
YVLPQ
1146
SEEGR
1151
GGGDN
1156
NPLDN
1161
LALEQ
1166
KDKST
1171
TFSVT
1176
IKTGV
1181
KKNAG
1186
TDANV
1191
FITLF
1196
GTQDD
1201
TGMTL
1206
LKSSK
1211
TNSDK
1216
FERDS
1221
IEIFT
1226
VETLD
1231
LGDLW
1236
KVRLG
1241
HDNTG
1246
KAPGW
1251
FVDWV
1256
EVDAP
1261
SLGKC
1266
MTFPC
1271
GRWLA
1276
KNEDD
1281
GSIIR
1286
DLFHA
1291
ELQTR
1296
LYTPF
1301
VPYEI
1306
TLYTS
1311
DVFAA
1316
GTDAN
1321
IFIII
1326
YGCDA
1331
VCTQQ
1336
KYLCT
1341
NKREQ
1346
KQFFE
1351
RKSAS
1356
RFIVE
1361
LEDVG
1366
EIIEK
1371
IRIGH
1376
NNTGM
1381
NPGWH
1386
CSHVD
1391
IRRLL
1396
PDKDG
1401
AETLT
1406
FPCDR
1411
WLATS
1416
EDDKK
1421
TIREL
1426
VPYDI
1431
FTEKY
1436
MKDGS
1441
LRQVY
1446
KEVEE
1451
PLDIV
1456
LYSVQ
1461
IFTGN
1466
IPGAG
1471
TDAKV
1476
YITIY
1481
GDLGD
1486
TGERY
1491
LGKSE
1496
NRTNK
1501
FERGT
1506
ADTFI
1511
IEAAD
1516
LGVIY
1521
KIKLR
1526
HDNSK
1531
WCADW
1536
YVEKV
1541
EIWND
1546
TNEDE
1551
FLFLC
1556
GRWLS
1561
LKKED
1566
GRLER
1571
LFYEK
1576
EYTGD
1581
RSSNC
1586
SSPAD
1591
FWEIA
1596
LSSKM
1601
ADVDI
1606
STVTG
1611
PMADY
1616
VQEGP
1621
IIPYY
1626
VSVTT
1631
GKHKD
1636
AATDS
1641
RAFIF
1646
LIGED
1651
DERSK
1656
RIWLD
1661
YPRGK
1666
RGFSR
1671
GSVEE
1676
FYVAG
1681
LDVGI
1686
IKKIE
1691
VLYEM
1696
TVWTG
1701
DVVGG
1706
GTDSN
1711
IFMTL
1716
YGING
1721
STEEM
1726
QLDKK
1731
KARFE
1736
REQND
1741
TFIME
1746
ILDIA
1751
PFTKM
1756
RIRID
1761
GLGSR
1766
PEWFL
1771
ERILL
1776
KNMNT
1781
GDLTM
1786
FYYGD
1791
WLSQR
1796
KGKKT
1801
LVCEM
1806
CAVID
1811
EEEMM
1816
EWTSY
1821
TVAVK
1826
TSDIL
1831
GAGTD
1836
ANVFI
1841
IIFGE
1846
NGDSG
1851
TLALK
1856
QSANW
1861
NKFER
1866
NNTDT
1871
FNFPD
1876
MLSLG
1881
HLCKL
1886
RVWHD
1891
NKGIF
1896
PGWHL
1901
SYVDV
1906
KDNSR
1911
DETFH
1916
FQCDC
1921
WLSKS
1926
EGDGQ
1931
TVRDF
1936
ACANN
1941
KICDE
1946
LEETT
1951
YEIVI
1956
ETGNG
1961
GETRE
1966
NVWLI
1971
LEGRK
1976
NRSKE
1981
FLMEN
1986
SSRQR
1991
AFRKG
1996
TTDTF
2001
EFDSI
2006
YLGDI
2011
ASLCV
2016
GHLAR
2021
EDRFI
2026
PKREL
2031
AWHVK
2036
TITIT
2041
EMEYG
2046
NVYFF
2051
NCDCL
2056
IPLKR
2061
KRKYF
2066
KVFEV
2071
TKTTE
2076
SFASK
2081
VQSLV
2086
PVKYE
2091
VIVTT
2096
GYEPG
2101
AGTDA
2106
NVFVT
2111
IFGAN
2116
GDTGK
2121
RELKQ
2126
KMRNL
2131
FERGS
2136
TDRFF
2141
LETLE
2146
LGELR
2151
KVRLE
2156
HDSSG
2161
YCSGW
2166
LVEKV
2171
EVTNT
2176
STGVA
2181
TIFNC
2186
GRWLD
2191
KKRGD
2196
GLTWR
2201
DLFPS
2206
V
2211
Mutation Information
DNA mutation:
None
Peptide Range:
1103 ~ 1127
Mut AA position:
1115 (13 in Wild Type peptide)
Alignment
Wild Type:
"FLDRIDITDMNNEITYYFPCQRWLA
||||||||||||.||||||||||||
Mutant:
FLDRIDITDMNNKITYYFPCQRWLA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) LOXHD1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay