Immunogenicity 5518

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
VANGL2
Transcript ID
NM_020335
HLA INFO
C*03:04
TCR INFO

No TCR info found!

T cell Tumor cell C*03:04
sequence
Full length protein sequence (521 aa)
MDTES
1
QYSGY
6
SYKSG
11
HSRSS
16
RKHRD
21
RRDRH
26
RSKSR
31
DGGRG
36
DKSVT
41
IQAPG
46
EPLLD
51
NESTR
56
GDERD
61
DNWGE
66
TTTVV
71
TGTSE
76
HSISH
81
DDLTR
86
IAKDM
91
EDSVP
96
LDCSR
101
HLGVA
106
AGATL
111
ALLSF
116
LTPLA
121
FLLLP
126
PLLWR
131
EELEP
136
CGTAC
141
EGLFI
146
SVAFK
151
LLILL
156
LGSWA
161
LFFRR
166
PKASL
171
PRVFV
176
LRALL
181
MVLVF
186
LLVVS
191
YWLFY
196
GVRIL
201
DARER
206
SYQGV
211
VQFAV
216
SLVDA
221
LLFVH
226
YLAVV
231
LLELR
236
QLQPQ
241
FTLKV
246
VRSTD
251
GASRF
256
YNVGH
261
LSIQR
266
VAVWI
271
LEKYY
276
HDFPV
281
YNPAL
286
LNLPK
291
SVLAK
296
KVSGF
301
KVYSL
306
GEENS
311
TNNST
316
GQSRA
321
VIAAA
326
ARRRD
331
NSHNE
336
YYYEE
341
AEHER
346
RVRKR
351
RARLV
356
VAVEE
361
AFTHI
366
KRLQE
371
EEQKN
376
PREVM
381
DPREA
386
AQAIF
391
ASMAR
396
AMQKY
401
LRTTK
406
QQPYH
411
TMESI
416
LQHLE
421
FCITH
426
DMTPK
431
AFLER
436
YLAAG
441
PTIQY
446
HKERW
451
LAKQW
456
TLVSE
461
EPVTN
466
GLKDG
471
IVFLL
476
KRQDF
481
SLVVS
486
TKKVP
491
FFKLS
496
EEFVD
501
PKSHK
506
FVMRL
511
QSETS
516
V
521
Mutation Information
DNA mutation:
None
Peptide Range:
352 ~ 376
Mut AA position:
364 (13 in Wild Type peptide)
Alignment
Wild Type:
"VRKRRARLVVAVEEAFTHIKRLQEE
||||||||||||.||||||||||||
Mutant:
VRKRRARLVVAVGEAFTHIKRLQEE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) VANGL2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay