Immunogenicity 5546

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PAX1
Transcript ID
NM_006192
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (534 aa)
MKFTL
1
GLGSR
6
AWRVS
11
WEGAA
16
AAAAG
21
PGAGG
26
SALRC
31
RAQRV
36
SSPRL
41
GRRGS
46
RLSGA
51
LPLCL
56
SRGGG
61
GAQAL
66
PDCAG
71
PSPGH
76
PGHPG
81
ARQLA
86
GPLAM
91
EQTYG
96
EVNQL
101
GGVFV
106
NGRPL
111
PNAIR
116
LRIVE
121
LAQLG
126
IRPCD
131
ISRQL
136
RVSHG
141
CVSKI
146
LARYN
151
ETGSI
156
LPGAI
161
GGSKP
166
RVTTP
171
NVVKH
176
IRDYK
181
QGDPG
186
IFAWE
191
IRDRL
196
LADGV
201
CDKYN
206
VPSVS
211
SISRI
216
LRNKI
221
GSLAQ
226
PGPYE
231
ASKQP
236
PSQPT
241
LPYNH
246
IYQYP
251
YPSPV
256
SPTGA
261
KMGSH
266
PGVPG
271
TAGHV
276
SIPRS
281
WPSAH
286
SVSNI
291
LGIRT
296
FMEQT
301
GALAG
306
SEGTA
311
YSPKM
316
EDWAG
321
VNRTA
326
FPATP
331
AVNGL
336
EKPAL
341
EADIK
346
YTQSA
351
STLSA
356
VGGFL
361
PACAY
366
PASNQ
371
HGVYS
376
APGGG
381
YLAPG
386
PPWPP
391
AQGPP
396
LAPPG
401
AGVAV
406
HGGEL
411
AAAMT
416
FKHPS
421
REGSL
426
PAPAA
431
RPRTP
436
SVAYT
441
DCPSR
446
PRPPR
451
GSSPR
456
TRARR
461
ERQAD
466
PGAQV
471
CAAAP
476
AIGTG
481
RIGGL
486
AEEEA
491
SAGPR
496
GARPA
501
SPQAQ
506
PCLWP
511
DPPHF
516
LYWSG
521
FLGFS
526
ELGF
531
Mutation Information
DNA mutation:
None
Peptide Range:
345 ~ 369
Mut AA position:
357 (13 in Wild Type peptide)
Alignment
Wild Type:
"LEADIKYTQSASTLSAVGGFLPACA
||||||||||||.||||||||||||
Mutant:
LEADIKYTQSASPLSAVGGFLPACA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PAX1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay