Immunogenicity 5560

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
KIF18B
Transcript ID
NM_001264573
HLA INFO
C*03:04
TCR INFO

No TCR info found!

T cell Tumor cell C*03:04
sequence
Full length protein sequence (833 aa)
MAVED
1
STLQV
6
VVRVR
11
PPTPR
16
ELDSQ
21
RRPVV
26
QVVDE
31
RVLVF
36
NPEEP
41
DGGFP
46
GLKWG
51
GTHDG
56
PKKKG
61
KDLTF
66
VFDRV
71
FGEAA
76
TQQDV
81
FQHTT
86
HSVLD
91
SFLQG
96
YNCSV
101
FAYGA
106
TGAGK
111
THTML
116
GREGD
121
PGIMY
126
LTTVE
131
LYRRL
136
EARQQ
141
EKHFE
146
VLISY
151
QEVYN
156
EQIHD
161
LLEPK
166
GPLAI
171
REDPD
176
KGVVV
181
QGLSF
186
HQPAS
191
AEQLL
196
EILTR
201
GNRNR
206
TQHPT
211
DANAT
216
SSRSH
221
AIFQI
226
FVKQQ
231
DRVPG
236
LTQAV
241
QVAKM
246
SLIDL
251
AGSER
256
ASSTH
261
AKGER
266
LREGA
271
NINRS
276
LLALI
281
NVLNA
286
LADAK
291
GRKTH
296
VPYRD
301
SKLTR
306
LLKDS
311
LGGNC
316
RTVMI
321
AAISP
326
SSLTY
331
EDTYN
336
TLKYA
341
DRAKE
346
IRLSL
351
KSNVT
356
SLDCH
361
ISQYA
366
TICQQ
371
LQAEV
376
AALRK
381
KLQVY
386
EGGGQ
391
PPPQD
396
LPGSP
401
KSGPP
406
PEHLP
411
SSPLP
416
PHPPS
421
QPCTP
426
ELPAG
431
PRALQ
436
EESLG
441
MEAQV
446
ERAME
451
GNSSD
456
QEQSP
461
EDEDE
466
GPAEE
471
VPTQM
476
PEQNP
481
THALP
486
ESPRL
491
TLQPK
496
PVVGH
501
FSARE
506
LDGDR
511
SKQLA
516
LKVLC
521
VAQRQ
526
YSLLQ
531
AANLL
536
TPDMI
541
TEFET
546
LQQLV
551
QEEKI
556
EPGAE
561
ALRTS
566
GLARG
571
APLAQ
576
ELCSE
581
SIPVP
586
SPLCP
591
EPPGY
596
TGPVT
601
RTMAR
606
RLSGP
611
LHTLG
616
IPPGP
621
NCTPA
626
QGSRW
631
PMEKK
636
RRRPS
641
ALEAD
646
SPMAP
651
KRGTK
656
RQRQS
661
FLPCL
666
RRGSL
671
PDTQP
676
SQGPS
681
TPKGE
686
RASSP
691
CHSPR
696
VCPAT
701
VIKSR
706
VPLGP
711
SAMQN
716
CSTPL
721
ALPTR
726
DLNAT
731
FDLSE
736
EPPSK
741
PSFHE
746
CIGWD
751
KIPQE
756
LSRLD
761
QPFIP
766
RAPVP
771
LFTMK
776
GPKPT
781
SSLPG
786
TSACK
791
KKRVA
796
SSSVS
801
HGRSR
806
IARLP
811
SSTLK
816
RPAGP
821
LVLPG
826
DWH
831
Mutation Information
DNA mutation:
None
Peptide Range:
203 ~ 227
Mut AA position:
215 (13 in Wild Type peptide)
Alignment
Wild Type:
"LTRGNRNRTQHPTDANATSSRSHAI
||||||||||||.||||||||||||
Mutant:
LTRGNRNRTQHPIDANATSSRSHAI"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KIF18B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay