Immunogenicity 5564

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KCNH6
Transcript ID
NM_173092
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (905 aa)
MPVRR
1
GHVAP
6
QNTYL
11
DTIIR
16
KFEGQ
21
SRKFL
26
IANAQ
31
MENCA
36
IIYCN
41
DGFCE
46
LFGYS
51
RVEVM
56
QQPCT
61
CDFLT
66
GPNTP
71
SSAVS
76
RLAQA
81
LLGAE
86
ECKVD
91
ILYYR
96
KDASS
101
FRCLV
106
DVVPV
111
KNEDG
116
AVIMF
121
ILNFE
126
DLAQL
131
LAKCS
136
SRSLS
141
QRLLS
146
QSFLG
151
SEGSH
156
GRPGG
161
PGPGT
166
GRGKY
171
RTISQ
176
IPQFT
181
LNFVE
186
FNLEK
191
HRSSS
196
TTEIE
201
IIAPH
206
KVVER
211
TQNVT
216
EKVTQ
221
VLSLG
226
ADVLP
231
EYKLQ
236
APRIH
241
RWTIL
246
HYSPF
251
KAVWD
256
WLILL
261
LVIYT
266
AVFTP
271
YSAAF
276
LLSDQ
281
DESRR
286
GACSY
291
TCSPL
296
TVVDL
301
IVDIM
306
FVVDI
311
VINFR
316
TTYVN
321
TNDEV
326
VSHPR
331
RIAVH
336
YFKGW
341
FLIDM
346
VAAIP
351
FDLLI
356
FRTGS
361
DETTT
366
LIGLL
371
KTARL
376
LRLVR
381
VARKL
386
DRYSE
391
YGAAV
396
LFLLM
401
CTFAL
406
IAHWL
411
ACICS
416
LTSVG
421
FGNVS
426
PNTNS
431
EKVFS
436
ICVML
441
IGSLM
446
YASIF
451
GNVSA
456
IIQRL
461
YSGTA
466
RYHTQ
471
MLRVK
476
EFIRF
481
HQIPN
486
PLRQR
491
LEEYF
496
QHAWS
501
YTNGI
506
DMNAV
511
LKGFP
516
ECLQA
521
DICLH
526
LHRAL
531
LQHCP
536
AFSGA
541
GKGCL
546
RALAV
551
KFKTT
556
HAPPG
561
DTLVH
566
LGDVL
571
STLYF
576
ISRGS
581
IEILR
586
DDVVV
591
AILGK
596
NDIFG
601
EPVSL
606
HAQPG
611
KSSAD
616
VRALT
621
YCDLH
626
KIQRA
631
DLLEV
636
LDMYP
641
AFAES
646
FWSKL
651
EVTFN
656
LRDAA
661
GGLHS
666
SPRQA
671
PGSQD
676
HQGFF
681
LSDNQ
686
SDAAP
691
PLSIS
696
DASGL
701
WPELL
706
QEMPP
711
RHSPQ
716
SPQED
721
PDCWP
726
LKLGS
731
RLEQL
736
QAQMN
741
RLESR
746
VSSDL
751
SRILQ
756
LLQKP
761
MPQGH
766
ASYIL
771
EAPAS
776
NDLAL
781
VPIAS
786
ETTSP
791
GPRLP
796
QGFLP
801
PAQTP
806
SYGDL
811
DDCSP
816
KHRNS
821
SPRMP
826
HLAVA
831
TDKTL
836
APSSE
841
QEQPE
846
GLWPP
851
LASPL
856
HPLEV
861
QGLIC
866
GPCFS
871
SLPEH
876
LGSVP
881
KQLDF
886
QRHGS
891
DPGFA
896
GSWGH
901
Mutation Information
DNA mutation:
None
Peptide Range:
351 ~ 375
Mut AA position:
363 (13 in Wild Type peptide)
Alignment
Wild Type:
"VAAIPFDLLIFRTGSDETTTLIGLL
||||||||||||.||||||||||||
Mutant:
VAAIPFDLLIFRNGSDETTTLIGLL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KCNH6

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay