Immunogenicity 5576

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LARP1
Transcript ID
NM_015315
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (1019 aa)
MLWRV
1
LLSKR
6
PPFPH
11
PELDF
16
QEAPI
21
PSCPG
26
RLPGR
31
KNSVA
36
LAAAP
41
RKEPT
46
GDREK
51
PLPFP
56
VLAPF
61
SNPEH
66
SAPAK
71
VVRAA
76
VPKQR
81
KGSKV
86
GDFGD
91
AINWP
96
TPGEI
101
AHKSV
106
QPQSH
111
KPQPT
116
RKLPP
121
KKDMK
126
EQEKG
131
EGSDS
136
KESPK
141
TKSDE
146
SGEEK
151
NGDED
156
CQRGG
161
QKKKG
166
NKHKW
171
VPLQI
176
DMKPE
181
VPREK
186
LASRP
191
TRPPE
196
PRHIP
201
ANRGE
206
IKGSE
211
SATYV
216
PVAPP
221
TPAWQ
226
PEIKP
231
EPAWH
236
DQDET
241
SSVKS
246
DGAGG
251
ARASF
256
RGRGR
261
GRGRG
266
RGRGR
271
GGTRT
276
HFDYQ
281
FGYRK
286
FDGVE
291
GPRTP
296
KYMNN
301
ITYYF
306
DNVSS
311
TELYS
316
VDQEL
321
LKDYI
326
KRQIE
331
YYFSV
336
DNLER
341
DFFLR
346
RKMDA
351
DGFLP
356
ITLIA
361
SFHRV
366
QALTT
371
DISLI
376
FAALK
381
DSKVV
386
EIVDE
391
KVRRR
396
EEPEK
401
WPLPP
406
IVDYS
411
QTDFS
416
QLLNC
421
PEFVP
426
RQHYQ
431
KETES
436
APGSP
441
RAVTP
446
VPTKT
451
EEVSN
456
LKTLP
461
KGLSA
466
SLPDL
471
DSENW
476
IEVKK
481
RPRPS
486
PARPK
491
KSEES
496
RFSHL
501
TSLPQ
506
QLPSQ
511
QLMSK
516
DQDEQ
521
EELDF
526
LFDEE
531
MEQMD
536
GRKNT
541
FTAWS
546
DEESD
551
YEIDD
556
RDVNK
561
ILIVT
566
QTPHY
571
MRRHP
576
GGDRT
581
GNHTS
586
RAKMS
591
AELAK
596
VINDG
601
LFYYE
606
QDLWA
611
EKFEP
616
EYSQI
621
KQEVE
626
NFKKV
631
NMISR
636
EQFDT
641
LTPEP
646
PVDPN
651
QEVPP
656
GPPRF
661
QQVPT
666
DALAN
671
KLFGA
676
PEPST
681
IARSL
686
PTTVP
691
ESPNY
696
RNTRT
701
PRTPR
706
TPQLK
711
DSSQT
716
SRFYP
721
VVKEG
726
RTLDA
731
KMPRK
736
RKTRH
741
SSNPP
746
LESHV
751
GWVMD
756
SREHR
761
PRTAS
766
ISSSP
771
SEGTP
776
TVGSY
781
GCTPQ
786
SLPKF
791
QHPSH
796
ELLKE
801
NGFTQ
806
HVYHK
811
YRRRC
816
LNERK
821
RLGIG
826
QSQEM
831
NTLFR
836
FWSFF
841
LRDHF
846
NKKMY
851
EEFKQ
856
LALED
861
AKEGY
866
RYGLE
871
CLFRY
876
YSYGL
881
EKKFR
886
LDIFK
891
DFQEE
896
TVKDY
901
EAGQL
906
YGLEK
911
FWAFL
916
KYSKA
921
KNLDI
926
DPKLQ
931
EYLGK
936
FRRLE
941
DFRVD
946
PPMGE
951
EGNHK
956
RHSVV
961
AGGGG
966
GEGRK
971
RCPSQ
976
SSSRP
981
AAMIS
986
QPPTP
991
PTGQP
996
VREDA
1001
KWTSQ
1006
HSNTQ
1011
TLGK
1016
Mutation Information
DNA mutation:
None
Peptide Range:
191 ~ 215
Mut AA position:
203 (13 in Wild Type peptide)
Alignment
Wild Type:
"LASRPTRPPEPRHIPANRGEIKGSE
||||||||||||.||||||||||||
Mutant:
LASRPTRPPEPRPIPANRGEIKGSE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LARP1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay