Immunogenicity 56
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
MYH4
Transcript ID
uc002gmn.3
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1939 aa)
MSSDS
1
EMAIF
6
GEAAP
11
FLRKS
16
EKERI
21
EAQNK
26
PFDAK
31
TSVFV
36
VDPKE
41
SYVKA
46
IVQSR
51
EGGKV
56
TAKTE
61
AGATV
66
TVKED
71
QVFSM
76
NPPKY
81
DKIED
86
MAMMT
91
HLHEP
96
AVLYN
101
LKERY
106
AAWMI
111
YTYSG
116
LFCVT
121
VNPYK
126
WLPVY
131
NPEVV
136
TAYRG
141
KKRQE
146
APPHI
151
FSISD
156
NAYQF
161
MLTDR
166
ENQSI
171
LITGE
176
SGAGK
181
TVNTK
186
RVIQY
191
FATIA
196
VTGEK
201
KKEEP
206
ASGKM
211
QGTLE
216
DQIIS
221
ANPLL
226
EAFGN
231
AKTVR
236
NDNSS
241
RFGKF
246
IRIHF
251
GATGK
256
LASAD
261
IETYL
266
LEKSR
271
VTFQL
276
KAERS
281
YHIFY
286
QILSN
291
KKPEL
296
IEMLL
301
ITTNP
306
YDFAF
311
VSQGE
316
ITVPS
321
IDDQE
326
ELMAT
331
DSAVD
336
ILGFT
341
ADEKV
346
AIYKL
351
TGAVM
356
HYGNM
361
KFKQK
366
QREEQ
371
AEPDG
376
TEVAD
381
KAAYL
386
TSLNS
391
ADLLK
396
SLCYP
401
RVKVG
406
NEFVT
411
KGQTV
416
QQVYN
421
AVGAL
426
AKAIY
431
EKMFL
436
WMVTR
441
INQQL
446
DTKQP
451
RQYFI
456
GVLDI
461
AGFEI
466
FDFNS
471
LEQLC
476
INFTN
481
EKLQQ
486
FFNHH
491
MFVLE
496
QEEYK
501
KEGIE
506
WEFID
511
FGMDL
516
AACIE
521
LIEKP
526
MGIFS
531
ILEEE
536
CMFPK
541
ATDTS
546
FKNKL
551
YEQHL
556
GKSNN
561
FQKPK
566
PAKGK
571
PEAHF
576
SLVHY
581
AGTVD
586
YNIAG
591
WLDKN
596
KDPLN
601
ETVVG
606
LYQKS
611
AMKTL
616
AFLFS
621
GAQTA
626
EAEGG
631
GGKKG
636
GKKKG
641
SSFQT
646
VSALF
651
RENLN
656
KLMTN
661
LRSTH
666
PHFVR
671
CIIPN
676
ETKTP
681
GAMEH
686
ELVLH
691
QLRCN
696
GVLEG
701
IRICR
706
KGFPS
711
RILYA
716
DFKQR
721
YKVLN
726
ASAIP
731
EGQFI
736
DSKKA
741
SEKLL
746
GSIEI
751
DHTQY
756
KFGHT
761
KVFFK
766
AGLLG
771
TLEEM
776
RDEKL
781
AQLIT
786
RTQAI
791
CRGFL
796
MRVEF
801
RKMME
806
RRESI
811
FCIQY
816
NIRAF
821
MNVKH
826
WPWMK
831
LYFKI
836
KPLLK
841
SAETE
846
KEMAN
851
MKEEF
856
EKTKE
861
ELAKT
866
EAKRK
871
ELEEK
876
MVTLM
881
QEKND
886
LQLQV
891
QAEAD
896
ALADA
901
EERCD
906
QLIKT
911
KIQLE
916
AKIKE
921
VTERA
926
EDEEE
931
INAEL
936
TAKKR
941
KLEDE
946
CSELK
951
KDIDD
956
LELTL
961
AKVEK
966
EKHAT
971
ENKVK
976
NLTEE
981
MAGLD
986
ETIAK
991
LTKEK
996
KALQE
1001
AHQQT
1006
LDDLQ
1011
MEEDK
1016
VNTLT
1021
KAKTK
1026
LEQQV
1031
DDLEG
1036
SLEQE
1041
KKLCM
1046
DLERA
1051
KRKLE
1056
GDLKL
1061
AQEST
1066
MDTEN
1071
DKQQL
1076
NEKLK
1081
KKEFE
1086
MSNLQ
1091
GKIED
1096
EQALA
1101
IQLQK
1106
KIKEL
1111
QARIE
1116
ELEEE
1121
IEAER
1126
ASRAK
1131
AEKQR
1136
SDLSR
1141
ELEEI
1146
SERLE
1151
EAGGA
1156
TSAQI
1161
EMNKK
1166
REAEF
1171
QKMRR
1176
DLEES
1181
TLQHE
1186
ATAAA
1191
LRKKH
1196
ADSVA
1201
ELGEQ
1206
IDSLQ
1211
RVKQK
1216
LEKEK
1221
SELKM
1226
EINDL
1231
ASNME
1236
TVSKA
1241
KANFE
1246
KMCRT
1251
LEDQL
1256
SEIKT
1261
KEEEQ
1266
QRLIN
1271
ELSAQ
1276
KARLH
1281
TESGE
1286
FSRQL
1291
DEKDA
1296
MVSQL
1301
SRGKQ
1306
AFTQQ
1311
IEELK
1316
RQLEE
1321
ETKAK
1326
STLAH
1331
ALQSA
1336
RHDCD
1341
LLREQ
1346
YEEEQ
1351
EAKAE
1356
LQRGM
1361
SKANS
1366
EVAQW
1371
RTKYE
1376
TDAIQ
1381
RTEEL
1386
EEAKK
1391
KLAQR
1396
LQDAE
1401
EHVEA
1406
VNSKC
1411
ASLEK
1416
TKQRL
1421
QNEVE
1426
DLMID
1431
VERSN
1436
AACIA
1441
LDKKQ
1446
RNFDK
1451
VLAEW
1456
KQKYE
1461
ETQAE
1466
LEASQ
1471
KESRS
1476
LSTEL
1481
FKVKN
1486
AYEES
1491
LDHLE
1496
TLKRE
1501
NKNLQ
1506
QEISD
1511
LTEQI
1516
AEGGK
1521
HIHEL
1526
EKVKK
1531
QLDHE
1536
KSELQ
1541
TSLEE
1546
AEASL
1551
EHEEG
1556
KILRI
1561
QLELN
1566
QVKSE
1571
IDRKI
1576
AEKDE
1581
ELDQL
1586
KRNHL
1591
RVVES
1596
MQSTL
1601
DAEIR
1606
SRNDA
1611
LRIKK
1616
KMEGD
1621
LNEME
1626
IQLNH
1631
ANRQA
1636
AEALR
1641
NLRNT
1646
QGILK
1651
DTQLH
1656
LDDAI
1661
RGQDD
1666
LKEQL
1671
AMVER
1676
RANLM
1681
QAEVE
1686
ELRAS
1691
LERTE
1696
RGRKM
1701
AEQEL
1706
LDASE
1711
RVQLL
1716
HTQNT
1721
SLINT
1726
KKKLE
1731
TDISQ
1736
IQGEM
1741
EDIVQ
1746
EARNA
1751
EEKAK
1756
KAITD
1761
AAMMA
1766
EELKK
1771
EQDTS
1776
AHLER
1781
MKKNM
1786
EQTVK
1791
DLQLR
1796
LDEAE
1801
QLALK
1806
GGKKQ
1811
IQKLE
1816
ARVRE
1821
LESEV
1826
ESEQK
1831
HNVEA
1836
VKGLR
1841
KHERR
1846
VKELT
1851
YQTEE
1856
DRKNI
1861
LRLQD
1866
LVDKL
1871
QTKVK
1876
AYKRQ
1881
AEEAE
1886
EQSNV
1891
NLAKF
1896
RKLQH
1901
ELEEA
1906
KERAD
1911
IAESQ
1916
VNKLR
1921
VKSRE
1926
VHTKV
1931
ISEE
1936
Mutation Information
DNA mutation:
c.G1279A
Peptide Range:
415 ~ 439
Mut AA position:
427 (13 in Wild Type peptide)
Alignment
Wild Type:
"TKGQTVQQVYNAVGALAKAIYEKMF
||||||||||||.||||||||||||
Mutant:
TKGQTVQQVYNAMGALAKAIYEKMF"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) MYH4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
TKGQTVQQVYNAMGALAKAIYEKMF
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT