Immunogenicity 5627

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ORC2
Transcript ID
NM_006190
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (577 aa)
MSKPE
1
LKEDK
6
MLEVH
11
FVGDD
16
DVLNH
21
ILDRE
26
GGAKL
31
KKERA
36
QLLVN
41
PKKII
46
KKPEY
51
DLEED
56
DQEVL
61
KDQNY
66
VEIMG
71
RDVQE
76
SLKNG
81
SATGG
86
GNKVY
91
SFQNR
96
KHSEK
101
MAKLA
106
SELAK
111
TPQKS
116
VSFSL
121
KNDPE
126
ITINV
131
PQSSK
136
GHSAS
141
DKVQP
146
KNNDK
151
SEFLS
156
TAPRS
161
LRKRL
166
IVPRS
171
HSDSE
176
SEYSA
181
SNSED
186
DEGVA
191
QEHEE
196
DTNAV
201
IFSQK
206
IQAQN
211
RVVSA
216
PVGKE
221
TPSKR
226
MKRDK
231
TSDLV
236
EEYFE
241
AHSSS
246
KVLTS
251
DRTLQ
256
KLKRA
261
KLDQQ
266
TLRNL
271
LSKVS
276
PSFSA
281
ELKQL
286
NQQYE
291
KLFHK
296
WMLQL
301
HLGFN
306
IVLYG
311
LGSKR
316
DLLER
321
FRTTM
326
LQDSI
331
HVVIN
336
GFFPG
341
ISVKS
346
VLNSI
351
TEEVL
356
DHMGT
361
FRSIL
366
DQLDW
371
IVNKF
376
KEDSS
381
LELFL
386
LIHNL
391
DSQML
396
RGEKS
401
QQIIG
406
QLSSL
411
HNIYL
416
IASID
421
HLNAP
426
LMWDH
431
AKQSL
436
FNWLW
441
YETTT
446
YSPYT
451
EETSY
456
ENSLL
461
VKQSG
466
SLPLS
471
SLTHV
476
LRSLT
481
PNARG
486
IFRLL
491
IKYQL
496
DNQDN
501
PSYIG
506
LSFQD
511
FYQQC
516
REAFL
521
VNSDL
526
TLRAQ
531
LTEFR
536
DHKLI
541
RTKKG
546
TDGVE
551
YLLIP
556
VDNGT
561
LTDFL
566
EKEEE
571
EA
576
Mutation Information
DNA mutation:
None
Peptide Range:
560 ~ 577
Mut AA position:
572 (13 in Wild Type peptide)
Alignment
Wild Type:
"PVDNGTLTDFLEKEEEEA
||||||||||||.|||||
Mutant:
PVDNGTLTDFLEREEEEA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ORC2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay