Immunogenicity 5628

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CSPP1
Transcript ID
NM_024790
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (1221 aa)
MLFPL
1
QVAAV
6
TSSVR
11
DDPLE
16
HCVSP
21
RTRAR
26
SPEIC
31
KMADN
36
LDEFI
41
EEQKA
46
RLAED
51
KAELE
56
SDPPY
61
MEMKG
66
KLSAK
71
LSENS
76
KILIS
81
MAKEN
86
IPPNS
91
QQTRG
96
SLGID
101
YGLSL
106
PLGED
111
YERKK
116
HKLKE
121
ELRQD
126
YRRYL
131
TQERL
136
KLERN
141
KEYNQ
146
FLRGK
151
EESSE
156
KFRQV
161
EKSTE
166
PKSQR
171
NKKPI
176
GQVKP
181
DLTSQ
186
IQTSC
191
ENSEG
196
PRKDV
201
LTPSE
206
AYEEL
211
LNQRR
216
LEEDR
221
YRQLD
226
DEIEL
231
RNRRI
236
IKKAN
241
EEVGI
246
SNLKH
251
QRFAS
256
KAGIP
261
DRRFH
266
RFNED
271
RVFDR
276
RYHRP
281
DQDPE
286
VSEEM
291
DERFR
296
YESDF
301
DRRLS
306
RVYTN
311
DRMHR
316
NKRGN
321
MPPME
326
HDGDV
331
IEQSN
336
IRISS
341
AENKS
346
APDNE
351
TSKSA
356
NQDTC
361
SPFAG
366
MLFGG
371
EDREL
376
IQRRK
381
EKYRL
386
ELLEQ
391
MAEQQ
396
RNKRR
401
EKDLE
406
LRVAA
411
SGAQD
416
PEKSP
421
DRLKQ
426
FSVAP
431
RHFEE
436
MIPPE
441
RPRIA
446
FQTPL
451
PPLSA
456
PSVPP
461
IPSVH
466
PVPSQ
471
NEDLR
476
SGLSS
481
ALGEM
486
VSPRI
491
APLPP
496
PPLLP
501
PLATN
506
YRTPY
511
DDAYY
516
FYGSR
521
NTFDP
526
SLAYY
531
GSGMM
536
GVQPA
541
AYVSA
546
PVTHQ
551
LAQPV
556
VNTVG
561
QNELK
566
ITSDQ
571
VINSG
576
LIFED
581
KPKPS
586
KQSLQ
591
SYQEA
596
LQQQI
601
REREE
606
RRKKE
611
REEKE
616
EYEAK
621
LEAEM
626
RTYNP
631
WGKGG
636
GGAPL
641
RDAKG
646
NLITD
651
LNRMH
656
RQNID
661
AYHNP
666
DARTY
671
EDKRA
676
VVSLD
681
PNLAT
686
SNAEN
691
LEDAA
696
NKSSG
701
HMQTQ
706
SSPFA
711
RGNVF
716
GEPPT
721
ELQIK
726
QQELY
731
KNFLR
736
FQIEE
741
KKQRE
746
EAERE
751
RLRIA
756
EEKEE
761
RRLAE
766
QRARI
771
QQEYE
776
EEQEK
781
KREKE
786
EEQRL
791
KNEEH
796
IRLAE
801
ERQKE
806
AERKK
811
KEEEE
816
KYNLQ
821
LQHYC
826
ERDNL
831
IGEET
836
KHMRQ
841
PSPIV
846
PALQN
851
KIASK
856
LQRPP
861
SVDSI
866
IRSFI
871
HESSM
876
SRAQS
881
PPVPA
886
RKNQL
891
RAEEE
896
KKNVI
901
MELSE
906
MRKQL
911
RSEER
916
RLQER
921
LLHMD
926
SDDEI
931
PIRKK
936
ERNPM
941
DIFDM
946
ARHRL
951
QAPVR
956
RQSPK
961
GLDAA
966
TFQNV
971
HDFNE
976
LKDRD
981
SETRV
986
DLKFM
991
YLDPP
996
RDHHT
1001
LEIQQ
1006
QALLR
1011
EQQKR
1016
LNRIK
1021
MQEGA
1026
KVDLD
1031
AIPSA
1036
KVREQ
1041
RMPRD
1046
DTSDF
1051
LKNSL
1056
LESDS
1061
AFIGA
1066
YGETY
1071
PAIED
1076
DVLPP
1081
PSQLP
1086
SARER
1091
RRNKW
1096
KGLDI
1101
DSSRP
1106
NVAPD
1111
GLSLK
1116
SISSV
1121
NVDEL
1126
RVRNE
1131
ERMRR
1136
LNEFH
1141
NKPIN
1146
TDDES
1151
SLVDP
1156
DDIMK
1161
HIGDD
1166
GSNSV
1171
ATEPW
1176
LRPGT
1181
SETLK
1186
RFMAE
1191
QLNQE
1196
QQQIP
1201
GKPGT
1206
FTWQG
1211
LSTAH
1216
G
1221
Mutation Information
DNA mutation:
None
Peptide Range:
932 ~ 956
Mut AA position:
944 (13 in Wild Type peptide)
Alignment
Wild Type:
"DDEIPIRKKERNPMDIFDMARHRLQ
||||||||||||.||||||||||||
Mutant:
DDEIPIRKKERNLMDIFDMARHRLQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CSPP1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay