Immunogenicity 5653

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DDX27
Transcript ID
NM_017895
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (796 aa)
MVLAQ
1
RRRGG
6
CEKLR
11
AGPQA
16
VLASG
21
SGFCD
26
NMLAD
31
LGLIG
36
TIGED
41
DEVPV
46
EPESD
51
SGDEE
56
EEGPI
61
VLGRR
66
QKALG
71
KNRSA
76
DFNPD
81
FVFTE
86
KEGTY
91
DGSWA
96
LADVM
101
SQLKK
106
KRAAT
111
TLDEK
116
IEKVR
121
KKRKT
126
EDKEA
131
KSGKL
136
EKEKE
141
AKEGS
146
EPKEQ
151
EDLQE
156
NDEEG
161
SEDEA
166
SETDY
171
SSADE
176
NILTK
181
ADTLK
186
VKDRK
191
KKKKK
196
GQEAG
201
GFFED
206
ASQYD
211
ENLSF
216
QDMNL
221
SRPLL
226
KAITA
231
MGFKQ
236
PTPIQ
241
KACIP
246
VGLLG
251
KDICA
256
CAATG
261
TGKTA
266
AFALP
271
VLERL
276
IYKPR
281
QAPVT
286
RVLVL
291
VPTRE
296
LGIQV
301
HSVTR
306
QLAQF
311
CNITT
316
CLAVG
321
GLDVK
326
SQEAA
331
LRAAP
336
DILIA
341
TPGRL
346
IDHLH
351
NCPSF
356
HLSSI
361
EVLIL
366
DEADR
371
MLDEY
376
FEEQM
381
KEIIR
386
MCSHH
391
RQTML
396
FSATM
401
TDEVK
406
DLASV
411
SLKNP
416
VRIFV
421
NSNTD
426
VAPFL
431
RQEFI
436
RIRPN
441
REGDR
446
EAIVA
451
ALLTR
456
TFTDH
461
VMLFT
466
QTKKQ
471
AHRMH
476
ILLGL
481
MGLQV
486
GELHG
491
NLSQT
496
QRLEA
501
LRRFK
506
DEQID
511
ILVAT
516
DVAAR
521
GLDIE
526
GVKTV
531
INFTM
536
PNTIK
541
HYVHR
546
VGRTA
551
RAGRA
556
GRSVS
561
LVGED
566
ERKML
571
KEIVK
576
AAKAP
581
VKARI
586
LPQDV
591
ILKFR
596
DKIEK
601
MEKDV
606
YAVLQ
611
LEAEE
616
KEMQQ
621
SEAQI
626
NTAKR
631
LLEKG
636
KEAVV
641
QEPER
646
SWFQT
651
KEERK
656
KEKIA
661
KALQE
666
FDLAL
671
RGKKK
676
RKKFM
681
KDAKK
686
KGEMT
691
AEERS
696
QFEIL
701
KAQMF
706
AERLA
711
KRNRR
716
AKRAR
721
AMPEE
726
EPVRG
731
PAKKQ
736
KQGKK
741
SVFDE
746
ELTNT
751
SKKAL
756
KQYRA
761
GPSFE
766
ERKQL
771
GLPHQ
776
RRGGN
781
FKSKS
786
RYKRR
791
K
796
Mutation Information
DNA mutation:
None
Peptide Range:
538 ~ 562
Mut AA position:
550 (13 in Wild Type peptide)
Alignment
Wild Type:
"FTMPNTIKHYVHRVGRTARAGRAGR
||||||||||||.||||||||||||
Mutant:
FTMPNTIKHYVHWVGRTARAGRAGR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DDX27

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay