Immunogenicity 5675

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
MAPKAPK2
Transcript ID
NM_032960
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (400 aa)
MLSNS
1
QGQSP
6
PVPFP
11
APAPP
16
PQPPT
21
PALPH
26
PPAQP
31
PPPPP
36
QQFPQ
41
FHVKS
46
GLQIK
51
KNAII
56
DDYKV
61
TSQVL
66
GLGIN
71
GKVLQ
76
IFNKR
81
TQEKF
86
ALKML
91
QDCPK
96
ARREV
101
ELHWR
106
ASQCP
111
HIVRI
116
VDVYE
121
NLYAG
126
RKCLL
131
IVMEC
136
LDGGE
141
LFSRI
146
QDRGD
151
QAFTE
156
REASE
161
IMKSI
166
GEAIQ
171
YLHSI
176
NIAHR
181
DVKPE
186
NLLYT
191
SKRPN
196
AILKL
201
TDFGF
206
AKETT
211
SHNSL
216
TTPCY
221
TPYYV
226
APEVL
231
GPEKY
236
DKSCD
241
MWSLG
246
VIMYI
251
LLCGY
256
PPFYS
261
NHGLA
266
ISPGM
271
KTRIR
276
MGQYE
281
FPNPE
286
WSEVS
291
EEVKM
296
LIRNL
301
LKTEP
306
TQRMT
311
ITEFM
316
NHPWI
321
MQSTK
326
VPQTP
331
LHTSR
336
VLKED
341
KERWE
346
DVKEE
351
MTSAL
356
ATMRV
361
DYEQI
366
KIKKI
371
EDASN
376
PLLLK
381
RRKKA
386
RALEA
391
AALAH
396
Mutation Information
DNA mutation:
None
Peptide Range:
347 ~ 371
Mut AA position:
359 (13 in Wild Type peptide)
Alignment
Wild Type:
"ERWEDVKEEMTSALATMRVDYEQIK
||||||||||||.||||||||||||
Mutant:
ERWEDVKEEMTSDLATMRVDYEQIK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MAPKAPK2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay