Immunogenicity 5682

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SLC25A5
Transcript ID
NM_001152
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (298 aa)
MTDAA
1
VSFAK
6
DFLAG
11
GVAAA
16
ISKTA
21
VAPIE
26
RVKLL
31
LQVQH
36
ASKQI
41
TADKQ
46
YKGII
51
DCVVR
56
IPKEQ
61
GVLSF
66
WRGNL
71
ANVIR
76
YFPTQ
81
ALNFA
86
FKDKY
91
KQIFL
96
GGVDK
101
RTQFW
106
LYFAG
111
NLASG
116
GAAGA
121
TSLCF
126
VYPLD
131
FARTR
136
LAADV
141
GKAGA
146
EREFR
151
GLGDC
156
LVKIY
161
KSDGI
166
KGLYQ
171
GFNVS
176
VQGII
181
IYRAA
186
YFGIY
191
DTAKG
196
MLPDP
201
KNTHI
206
VISWM
211
IAQTV
216
TAVAG
221
LTSYP
226
FDTVR
231
RRMMM
236
QSGRK
241
GTDIM
246
YTGTL
251
DCWRK
256
IARDE
261
GGKAF
266
FKGAW
271
SNVLR
276
GMGGA
281
FVLVL
286
YDEIK
291
KYT
296
Mutation Information
DNA mutation:
None
Peptide Range:
32 ~ 56
Mut AA position:
44 (13 in Wild Type peptide)
Alignment
Wild Type:
"VKLLLQVQHASKQITADKQYKGIID
||||||||||||.||||||||||||
Mutant:
VKLLLQVQHASKHITADKQYKGIID"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SLC25A5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay