Immunogenicity 57
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
AKAP1
Transcript ID
uc021uak.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (903 aa)
MAIQF
1
RSLFP
6
LALPG
11
MLALL
16
GWWWF
21
FSRKK
26
GHVSS
31
HDEQQ
36
VEAGA
41
VQLRA
46
DPAIK
51
EPLPV
56
EDVCP
61
KVVST
66
PPSVT
71
EPPEK
76
ELSTV
81
SKLPA
86
EPPAL
91
LQTHP
96
PCRRS
101
ESSGI
106
LPNTT
111
DMRLR
116
PGTRR
121
DDSTK
126
LELAL
131
TGGEA
136
KSIPL
141
ECPLS
146
SPKGV
151
LFSSK
156
SAEVC
161
KQDSP
166
FSRVP
171
RKVQP
176
GYPVV
181
PAEKR
186
SSGER
191
ARETG
196
GAEGT
201
GDAVL
206
GEKVL
211
EEALL
216
SREHV
221
LELEN
226
SKGPS
231
LASLE
236
GEEDK
241
GKSSS
246
SQVVG
251
PVQEE
256
EYVAE
261
KLPSR
266
FIESA
271
HTELA
276
KDDAA
281
PAPPV
286
ADAKA
291
QDRGV
296
EGELG
301
NEESL
306
DRNEE
311
GLDRN
316
EEGLD
321
RNEES
326
LDRNE
331
EGLDR
336
NEEIK
341
RAAFQ
346
IISQV
351
ISEAT
356
EQVLA
361
TTVGK
366
VAGRV
371
CQASQ
376
LQGQK
381
EESCV
386
PVHQK
391
TVLGP
396
DTAEP
401
ATAEA
406
AVAPP
411
DAGLP
416
LPGLP
421
AEGSP
426
PPKTY
431
VSCLK
436
SLLSS
441
PTKDS
446
KPNIS
451
AHHIS
456
LASCL
461
ALTTP
466
SEELP
471
DRAGI
476
LVEDA
481
TCVTC
486
MSDSS
491
QSVPL
496
VASPG
501
HCSDS
506
FSTSG
511
LEDSC
516
TETSS
521
SPRDK
526
AITPP
531
LPEST
536
VPFSN
541
GVLKG
546
ELSDL
551
GAEDG
556
WTMDA
561
EADHS
566
GGSDR
571
NSMDS
576
VDSCC
581
SLKKT
586
ESFQN
591
AQAGS
596
NPKKV
601
DLIIW
606
EIEVP
611
KHLVG
616
RLIGK
621
QGRYV
626
SFLKQ
631
TSGAK
636
IYIST
641
LPYTQ
646
SVQIC
651
HIEGS
656
QHHVD
661
KALNL
666
IGKKF
671
KELNL
676
TNIYA
681
PPLPS
686
LALPS
691
LPMTS
696
WLMLP
701
DGITV
706
EVIVV
711
NQVNA
716
GHLFV
721
QQHTH
726
PTFHA
731
LRSLD
736
QQMYL
741
CYSQP
746
GIPTL
751
PTPVE
756
ITVIC
761
AAPGA
766
DGAWW
771
RAQVV
776
ASYEE
781
TNEVE
786
IRYVD
791
YGGYK
796
RVKVD
801
VLRQI
806
RSDFV
811
TLPFQ
816
GAEVL
821
LDSVM
826
PLSDD
831
DQFSP
836
EADAA
841
MSEMT
846
GNTAL
851
LAQVT
856
SYSPT
861
GLPLI
866
QLWSV
871
VGDEV
876
VLINR
881
SLVER
886
GLAQW
891
VDSYY
896
TSL
901
Mutation Information
DNA mutation:
c.C1981G
Peptide Range:
649 ~ 673
Mut AA position:
661 (13 in Wild Type peptide)
Alignment
Wild Type:
"TQSVQICHIEGSQHHVDKALNLIGK
||||||||||||.||||||||||||
Mutant:
TQSVQICHIEGSEHHVDKALNLIGK"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) AKAP1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
TQSVQICHIEGSEHHVDKALNLIGK
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT