Immunogenicity 5701

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
EPB41L4B
Transcript ID
NM_019114
HLA INFO
B*14:01
TCR INFO

No TCR info found!

T cell Tumor cell B*14:01
sequence
Full length protein sequence (900 aa)
MLRFL
1
RRTFG
6
RRSMQ
11
RYARG
16
AAGRG
21
AAGLG
26
DERDG
31
GPRGG
36
PAAAA
41
SSSAL
46
PAAPG
51
GSVFP
56
AGGGP
61
LLTGG
66
AAVHI
71
SAAGA
76
AKATL
81
YCRVF
86
LLDGT
91
EVSVD
96
LPKHA
101
KGQDL
106
FDQIV
111
YHLDL
116
VETDY
121
FGLQF
126
LDSAQ
131
VAHWL
136
DHAKP
141
IKKQM
146
KIGPA
151
YALHF
156
RVKYY
161
SSEPN
166
NLREE
171
FTRYL
176
FVLQL
181
RHDIL
186
SGKLK
191
CPYET
196
AVELA
201
ALCLQ
206
AELGE
211
CELPE
216
HTPEL
221
VSEFR
226
FIPNQ
231
TEAME
236
FDIFQ
241
RWKEC
246
RGKSP
251
AQAEL
256
SYLNK
261
AKWLE
266
MYGVD
271
MHVVR
276
GRDGC
281
EYSLG
286
LTPTG
291
ILIFE
296
GANKI
301
GLFFW
306
PKITK
311
MDFKK
316
SKLTL
321
VVVED
326
DDQGR
331
EQEHT
336
FVFRL
341
DSART
346
CKHLW
351
KCAVE
356
HHAFF
361
RLRTP
366
GNSKS
371
NRSDF
376
IRLGS
381
RFRFS
386
GRTEY
391
QATHG
396
SRLRR
401
TSTFE
406
RKPSK
411
RYPSR
416
RHSTF
421
KASNP
426
VIAAQ
431
LCSKT
436
NPEVH
441
NYQPQ
446
YHPNI
451
HPSQP
456
RWHPH
461
SPNVS
466
YPLPS
471
PVLSS
476
SDRLP
481
FGIEE
486
NGGTP
491
FLTAA
496
SGRHH
501
HQHQH
506
QHQHQ
511
HHSNY
516
SLSLT
521
LENKE
526
GPLRS
531
PNSSS
536
KSLTK
541
LSPGT
546
PALFS
551
EAAAH
556
LKKLE
561
LETVK
566
AAGPW
571
PPLHI
576
NINKA
581
EEKKV
586
SEKTL
591
QTPLL
596
PSPVA
601
DHVKC
606
NILKA
611
QLENA
616
SRVNI
621
QGGKE
626
ESPFV
631
NINKK
636
SSLQD
641
ASVRS
646
PIPIR
651
VETAQ
656
PAVEK
661
PEIKP
666
PRVRK
671
LTRQY
676
SFDED
681
DLPPD
686
LAEAV
691
GVTTS
696
TTTNT
701
TTAAT
706
QVSVP
711
LPSPK
716
VQNVS
721
SPHKS
726
EGKGL
731
LSPGA
736
KSPSD
741
RGGAF
746
TLEPG
751
DLLMD
756
FTEAT
761
PLAEP
766
ASNPH
771
CAHSR
776
CSPPL
781
SLPMK
786
EETTG
791
VCMYP
796
PIKTR
801
LIKTF
806
PVDTM
811
NPFPD
816
TFTTG
821
PQFTA
826
DFRDS
831
KLQCC
836
PGPTS
841
PLIPA
846
ATLRP
851
LTETV
856
STVQT
861
IYTTR
866
KPVSL
871
AASAE
876
TLRQE
881
LEREK
886
MMKRL
891
LMTEL
896
Mutation Information
DNA mutation:
None
Peptide Range:
48 ~ 72
Mut AA position:
60 (13 in Wild Type peptide)
Alignment
Wild Type:
"SALPAAPGGSVFPAGGGPLLTGGAA
||||||||||||.||||||||||||
Mutant:
SALPAAPGGSVFRAGGGPLLTGGAA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) EPB41L4B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay