Immunogenicity 5731
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CUX2
Transcript ID
NM_015267
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO
No TCR info found!
Full length protein sequence (1486 aa)
MAANV
1
GSMFQ
6
YWKRF
11
DLRRL
16
QKELN
21
SVASE
26
LSARQ
31
EESEH
36
SHKHL
41
IELRR
46
EFKKN
51
VPEEI
56
REMVA
61
PVLKS
66
FQAEV
71
VALSK
76
RSQEA
81
EAAFL
86
SVYKQ
91
LIEAP
96
DPVPV
101
FEAAR
106
SLDDR
111
LQPPS
116
FDPSG
121
QPRRD
126
LHTSW
131
KRNPE
136
LLSPK
141
EQREG
146
TSPAG
151
PTLTE
156
GSRLP
161
GIPGK
166
ALLTE
171
TLLQR
176
NEAEK
181
QKGLQ
186
EVQIT
191
LAARL
196
GEAEE
201
KIKVL
206
HSALK
211
ATQAE
216
LLELR
221
RKYDE
226
EAASK
231
ADEVG
236
LIMTN
241
LEKAN
246
QRAEA
251
AQREV
256
ESLRE
261
QLASV
266
NSSIR
271
LACCS
276
PQGPS
281
GDKVN
286
FTLCS
291
GPRLE
296
AALAS
301
KDREI
306
LRLLK
311
DVQHL
316
QSSLQ
321
ELEEA
326
SANQI
331
ADLER
336
QLTAK
341
SEAIE
346
KLEEK
351
LQAQS
356
DYEEI
361
KTELS
366
ILKAM
371
KLASS
376
TCSLP
381
QGMAK
386
PEDSL
391
LIAKE
396
AFFPT
401
QKFLL
406
EKPSL
411
LASPE
416
EDPSE
421
DDSIK
426
DSLGT
431
EQSYP
436
SPQQL
441
PPPPG
446
PEDPL
451
SPSPG
456
QPLLG
461
PSLGP
466
DGTRT
471
FSLSP
476
FPSLA
481
SGERL
486
MMPPA
491
AFKGE
496
AGGLL
501
VFPPA
506
FYGAK
511
PPTAP
516
ATPAP
521
GPEPL
526
GGPEP
531
ADGGG
536
GGAAG
541
PGAEE
546
EQLDT
551
AEIAF
556
QVKEQ
561
LLKHN
566
IGQRV
571
FGHYV
576
LGLSQ
581
GSVSE
586
ILARP
591
KPWRK
596
LTVKG
601
KEPFI
606
KMKQF
611
LSDEQ
616
NVLAL
621
RTIQV
626
RQRGS
631
ITPRI
636
RTPET
641
GSDDA
646
IKSIL
651
EQAKK
656
EIESQ
661
KGGEP
666
KTSVA
671
PLSIA
676
NGTTP
681
ASTSE
686
DAIKS
691
ILEQA
696
RREMQ
701
AQQQA
706
LLEME
711
VAPRG
716
RSVPP
721
SPPER
726
PSLAT
731
ASQNG
736
APALV
741
KQEEG
746
SGGPA
751
QAPLP
756
VLSPA
761
AFVQS
766
IIRKV
771
KSEIG
776
DAGYF
781
DHHWA
786
SDRGL
791
LSRPY
796
ASVSP
801
SLSSS
806
SSSGY
811
SGQPN
816
GRAWP
821
RGDEA
826
PVPPE
831
DEAAA
836
GAEDE
841
PPRTG
846
ELKAE
851
GATAE
856
AGARL
861
PYYPA
866
YVPRT
871
LKPTV
876
PPLTP
881
EQYEL
886
YMYRE
891
VDTLE
896
LTRQV
901
KEKLA
906
KNGIC
911
QRIFG
916
EKVLG
921
LSQGS
926
VSDML
931
SRPKP
936
WSKLT
941
QKGRE
946
PFIRM
951
QLWLS
956
DQLGQ
961
AVGQQ
966
PGASQ
971
ASPTE
976
PRSSP
981
SPPPS
986
PTEPE
991
KSSQE
996
PLSLS
1001
LESSK
1006
ENQQP
1011
EGRSS
1016
SSLSG
1021
KMYSG
1026
SQAPG
1031
GIQEI
1036
VAMSP
1041
ELDTY
1046
SITKR
1051
VKEVL
1056
TDNNL
1061
GQRLF
1066
GESIL
1071
GLTQG
1076
SVSDL
1081
LSRPK
1086
PWHKL
1091
SLKGR
1096
EPFVR
1101
MQLWL
1106
NDPHN
1111
VEKLR
1116
DMKKL
1121
EKKAY
1126
LKRRY
1131
GLIST
1136
GSDSE
1141
SPATR
1146
SECPS
1151
PCLQP
1156
QDLSL
1161
LQIKK
1166
PRVVL
1171
APEEK
1176
EALRK
1181
AYQLE
1186
PYPSQ
1191
QTIEL
1196
LSFQL
1201
NLKTN
1206
TVINW
1211
FHNYR
1216
SRMRR
1221
EMLVE
1226
GTQDE
1231
PDLDP
1236
SGGPG
1241
ILPPG
1246
HSHPD
1251
PTPQS
1256
PDSET
1261
EDQKP
1266
TVKEL
1271
ELQEG
1276
PEENS
1281
TPLTT
1286
QDKAQ
1291
VRIKQ
1296
EQMEE
1301
DAEEE
1306
AGSQP
1311
QDSGE
1316
LDKGQ
1321
GPPKE
1326
EHPDP
1331
PGNDG
1336
LPKVA
1341
PGPLL
1346
PGGST
1351
PDCPS
1356
LHPQQ
1361
ESEAG
1366
ERLHP
1371
DPLSF
1376
KSASE
1381
SSRCS
1386
LEVSL
1391
NSPSA
1396
ASSPG
1401
LMMSV
1406
SPVPS
1411
SSAPI
1416
SPSPP
1421
GAPPA
1426
KVPSA
1431
SPTAD
1436
MAGAL
1441
HPSAK
1446
VNPNL
1451
QRRHE
1456
KMANL
1461
NNIIY
1466
RVERA
1471
ANREE
1476
ALEWE
1481
F
1486
Mutation Information
DNA mutation:
None
Peptide Range:
534 ~ 558
Mut AA position:
546 (13 in Wild Type peptide)
Alignment
Wild Type:
"EPADGGGGGAAGPGAEEEQLDTAEI
||||||||||||.||||||||||||
Mutant:
EPADGGGGGAAGAGAEEEQLDTAEI"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) CUX2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay