Immunogenicity 575

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TMPRSS15
Transcript ID
ENST00000284885
HLA INFO
C*01:02
TCR INFO

No TCR info found!

T cell Tumor cell C*01:02
sequence
Full length protein sequence (1019 aa)
MGSKR
1
GISSR
6
HHSLS
11
SYEIM
16
FAALF
21
AILVV
26
LCAGL
31
IAVSC
36
LTIKE
41
SQRGA
46
ALGQS
51
HEARA
56
TFKIT
61
SGVTY
66
NPNLQ
71
DKLSV
76
DFKVL
81
AFDLQ
86
QMIDE
91
IFLSS
96
NLKNE
101
YKNSR
106
VLQFE
111
NGSII
116
VVFDL
121
FFAQW
126
VSDEN
131
VKEEL
136
IQGLE
141
ANKSS
146
QLVTF
151
HIDLN
156
SVDIL
161
DKLTT
166
TSHLA
171
TPGNV
176
SIECL
181
PGSSP
186
CTDAL
191
TCIKA
196
DLFCD
201
GEVNC
206
PDGSD
211
EDNKM
216
CATVC
221
DGRFL
226
LTGSS
231
GSFQA
236
THYPK
241
PSETS
246
VVCQW
251
IIRVN
256
QGLSI
261
KLSFD
266
DFNTY
271
YTDIL
276
DIYEG
281
VGSSK
286
ILRAS
291
IWETN
296
PGTIR
301
IFSNQ
306
VTATF
311
LIESD
316
ESDYV
321
GFNAT
326
YTAFN
331
SSELN
336
NYEKI
341
NCNFE
346
DGFCF
351
WVQDL
356
NDDNE
361
WERIQ
366
GSTFS
371
PFTGP
376
NFDHT
381
FGNAS
386
GFYIS
391
TPTGP
396
GGRQE
401
RVGLL
406
SLPLD
411
PTLEP
416
ACLSF
421
WYHMY
426
GENVH
431
KLSIN
436
ISNDQ
441
NMEKT
446
VFQKE
451
GNYGD
456
NWNYG
461
QVTLN
466
ETVKF
471
KVAFN
476
AFKNK
481
ILSDI
486
ALDDI
491
SLTYG
496
ICNGS
501
LYPEP
506
TLVPT
511
PPPEL
516
PTDCG
521
GPFEL
526
WEPNT
531
TFSST
536
NFPNS
541
YPNLA
546
FCVWI
551
LNAQK
556
GKNIQ
561
LHFQE
566
FDLEN
571
INDVV
576
EIRDG
581
EEADS
586
LLLAV
591
YTGPG
596
PVKDV
601
FSTTN
606
RMTVL
611
LITND
616
VLARG
621
GFKAN
626
FTTGY
631
HLGIP
636
EPCKA
641
DHFQC
646
KNGEC
651
VPLVN
656
LCDGH
661
LHCED
666
GSDEA
671
DCVRF
676
FNGTT
681
NNNGL
686
VRFRI
691
QSIWH
696
TACAE
701
NWTTQ
706
ISNDV
711
CQLLG
716
LGSGN
721
SSKPI
726
FPTDG
731
GPFVK
736
LNTAP
741
DGHLI
746
LTPSQ
751
QCLQD
756
SLIRL
761
QCNHK
766
SCGKK
771
LAAQD
776
ITPKI
781
VGGSN
786
AKEGA
791
WPWVV
796
GLYYG
801
GRLLC
806
GASLV
811
SSDWL
816
VSAAH
821
CVYGR
826
NLEPS
831
KWTAI
836
LGLHM
841
KSNLT
846
SPQTV
851
PRLID
856
EIVIN
861
PHYNR
866
RRKDN
871
DIAMM
876
HLEFK
881
VNYTD
886
YIQPI
891
CLPEE
896
NQVFP
901
PGRNC
906
SIAGW
911
GTVVY
916
QGTTA
921
NILQE
926
ADVPL
931
LSNER
936
CQQQM
941
PEYNI
946
TENMI
951
CAGYE
956
EGGID
961
SCQGD
966
SGGPL
971
MCQEN
976
NRWFL
981
AGVTS
986
FGYKC
991
ALPNR
996
PGVYA
1001
RVSRF
1006
TEWIQ
1011
SFLH
1016
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 18
Mut AA position:
6 (6 in Wild Type peptide)
Alignment
Wild Type:
"MGSKRGISSRHHSLSSYEIMFAALF
|||||.||||||||||||
Mutant:
MGSKRDISSRHHSLSSYE-------"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TMPRSS15

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay