Immunogenicity 5806
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ITGB4
Transcript ID
NM_001005731
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1752 aa)
MAGPR
1
PSPWA
6
RLLLA
11
ALISV
16
SLSGT
21
LANRC
26
KKAPV
31
KSCTE
36
CVRVD
41
KDCAY
46
CTDEM
51
FRDRR
56
CNTQA
61
ELLAA
66
GCQRE
71
SIVVM
76
ESSFQ
81
ITEET
86
QIDTT
91
LRRSQ
96
MSPQG
101
LRVRL
106
RPGEE
111
RHFEL
116
EVFEP
121
LESPV
126
DLYIL
131
MDFSN
136
SMSDD
141
LDNLK
146
KMGQN
151
LARVL
156
SQLTS
161
DYTIG
166
FGKFV
171
DKVSV
176
PQTDM
181
RPEKL
186
KEPWP
191
NSDPP
196
FSFKN
201
VISLT
206
EDVDE
211
FRNKL
216
QGERI
221
SGNLD
226
APEGG
231
FDAIL
236
QTAVC
241
TRDIG
246
WRPDS
251
THLLV
256
FSTES
261
AFHYE
266
ADGAN
271
VLAGI
276
MSRND
281
ERCHL
286
DTTGT
291
YTQYR
296
TQDYP
301
SVPTL
306
VRLLA
311
KHNII
316
PIFAV
321
TNYSY
326
SYYEK
331
LHTYF
336
PVSSL
341
GVLQE
346
DSSNI
351
VELLE
356
EAFNR
361
IRSNL
366
DIRAL
371
DSPRG
376
LRTEV
381
TSKMF
386
QKTRT
391
GSFHI
396
RRGEV
401
GIYQV
406
QLRAL
411
EHVDG
416
THVCQ
421
LPEDQ
426
KGNIH
431
LKPSF
436
SDGLK
441
MDAGI
446
ICDVC
451
TCELQ
456
KEVRS
461
ARCSF
466
NGDFV
471
CGQCV
476
CSEGW
481
SGQTC
486
NCSTG
491
SLSDI
496
QPCLR
501
EGEDK
506
PCSGR
511
GECQC
516
GHCVC
521
YGEGR
526
YEGQF
531
CEYDN
536
FQCPR
541
TSGFL
546
CNDRG
551
RCSMG
556
QCVCE
561
PGWTG
566
PSCDC
571
PLSNA
576
TCIDS
581
NGGIC
586
NGRGH
591
CECGR
596
CHCHQ
601
QSLYT
606
DTICE
611
INYSA
616
IHPGL
621
CEDLR
626
SCVQC
631
QAWGT
636
GEKKG
641
RTCEE
646
CNFKV
651
KMVDE
656
LKRAE
661
EVVVR
666
CSFRD
671
EDDDC
676
TYSYT
681
MEGDG
686
APGPN
691
STVLV
696
HKKKD
701
CPPGS
706
FWWLI
711
PLLLL
716
LLPLL
721
ALLLL
726
LCWKY
731
CACCK
736
ACLAL
741
LPCCN
746
RGHMV
751
GFKED
756
HYMLR
761
ENLMA
766
SDHLD
771
TPMLR
776
SGNLK
781
GRDVV
786
RWKVT
791
NNMQR
796
PGFAT
801
HAASI
806
NPTEL
811
VPYGL
816
SLRLA
821
RLCTE
826
NLLKP
831
DTREC
836
AQLRQ
841
EVEEN
846
LNEVY
851
RQISG
856
VHKLQ
861
QTKFR
866
QQPNA
871
GKKQD
876
HTIVD
881
TVLMA
886
PRSAK
891
PALLK
896
LTEKQ
901
VEQRA
906
FHDLK
911
VAPGY
916
YTLTA
921
DQDAR
926
GMVEF
931
QEGVE
936
LVDVR
941
VPLFI
946
RPEDD
951
DEKQL
956
LVEAI
961
DVPAG
966
TATLG
971
RRLVN
976
ITIIK
981
EQARD
986
VVSFE
991
QPEFS
996
VSRGD
1001
QVARI
1006
PVIRR
1011
VLDGG
1016
KSQVS
1021
YRTQD
1026
GTAQG
1031
NRDYI
1036
PVEGE
1041
LLFQP
1046
GEAWK
1051
ELQVK
1056
LLELQ
1061
EVDSL
1066
LRGRQ
1071
VRRFH
1076
VQLSN
1081
PKFGA
1086
HLGQP
1091
HSTTI
1096
IIRDP
1101
DELDR
1106
SFTSQ
1111
MLSSQ
1116
PPPHG
1121
DLGAP
1126
QNPNA
1131
KAAGS
1136
RKIHF
1141
NWLPP
1146
SGKPM
1151
GYRVK
1156
YWIQG
1161
DSESE
1166
AHLLD
1171
SKVPS
1176
VELTN
1181
LYPYC
1186
DYEMK
1191
VCAYG
1196
AQGEG
1201
PYSSL
1206
VSCRT
1211
HQEVP
1216
SEPGR
1221
LAFNV
1226
VSSTV
1231
TQLSW
1236
AEPAE
1241
TNGEI
1246
TAYEV
1251
CYGLV
1256
NDDNR
1261
PIGPM
1266
KKVLV
1271
DNPKN
1276
RMLLI
1281
ENLRE
1286
SQPYR
1291
YTVKA
1296
RNGAG
1301
WGPER
1306
EAIIN
1311
LATQP
1316
KRPMS
1321
IPIIP
1326
DIPIV
1331
DAQSG
1336
EDYDS
1341
FLMYS
1346
DDVLR
1351
SPSGS
1356
QRPSV
1361
SDDTE
1366
HLVNG
1371
RMDFA
1376
FPGST
1381
NSLHR
1386
MTTTS
1391
AAAYG
1396
THLSP
1401
HVPHR
1406
VLSTS
1411
STLTR
1416
DYNSL
1421
TRSEH
1426
SHSTT
1431
LPRDY
1436
STLTS
1441
VSSHD
1446
SRLTA
1451
GVPDT
1456
PTRLV
1461
FSALG
1466
PTSLR
1471
VSWQE
1476
PRCER
1481
PLQGY
1486
SVEYQ
1491
LLNGG
1496
ELHRL
1501
NIPNP
1506
AQTSV
1511
VVEDL
1516
LPNHS
1521
YVFRV
1526
RAQSQ
1531
EGWGR
1536
EREGV
1541
ITIES
1546
QVHPQ
1551
SPLCP
1556
LPGSA
1561
FTLST
1566
PSAPG
1571
PLVFT
1576
ALSPD
1581
SLQLS
1586
WERPR
1591
RPNGD
1596
IVGYL
1601
VTCEM
1606
AQGGG
1611
PATAF
1616
RVDGD
1621
SPESR
1626
LTVPG
1631
LSENV
1636
PYKFK
1641
VQART
1646
TEGFG
1651
PEREG
1656
IITIE
1661
SQDGG
1666
PFPQL
1671
GSRAG
1676
LFQHP
1681
LQSEY
1686
SSITT
1691
THTSA
1696
TEPFL
1701
VDGLT
1706
LGAQH
1711
LEAGG
1716
SLTRH
1721
VTQEF
1726
VSRTL
1731
TTSGT
1736
LSTHM
1741
DQQFF
1746
QT
1751
Mutation Information
DNA mutation:
None
Peptide Range:
936 ~ 960
Mut AA position:
948 (13 in Wild Type peptide)
Alignment
Wild Type:
"QEGVELVDVRVPLFIRPEDDDEKQL
||||||||||||.||||||||||||
Mutant:
QEGVELVDVRVPVFIRPEDDDEKQL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ITGB4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay