Immunogenicity 5814

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KCTD3
Transcript ID
NM_016121
HLA INFO
B*13:02
TCR INFO

No TCR info found!

T cell Tumor cell B*13:02
sequence
Full length protein sequence (815 aa)
MAGGH
1
CGSFP
6
AAAAG
11
SGEIV
16
QLNVG
21
GTRFS
26
TSRQT
31
LMWIP
36
DSFFS
41
SLLSG
46
RISTL
51
RDETG
56
AIFID
61
RDPAA
66
FAPIL
71
NFLRT
76
KELDL
81
RGVSI
86
NVLRH
91
EAEFY
96
GITPL
101
VRRLL
106
LCEEL
111
ERSSC
116
GSVLF
121
HGYLP
126
PPGIP
131
SRKIN
136
NTVRS
141
ADSRN
146
GLNST
151
EGEAR
156
GNGTQ
161
PVLSG
166
TGEET
171
VRLGF
176
PVDPR
181
KVLIV
186
AGHHN
191
WIVAA
196
YAHFA
201
VCYRI
206
KESSG
211
WQQVF
216
TSPYL
221
DWTIE
226
RVALN
231
AKVVG
236
GPHGD
241
KDKMV
246
AVASE
251
SSIIL
256
WSVQD
261
GGSGS
266
EIGVF
271
SLGVP
276
VDALF
281
FIGNQ
286
LVATS
291
HTGKV
296
GVWNA
301
VTQHW
306
QVQDV
311
VPITS
316
YDTAG
321
SFLLL
326
GCNNG
331
SIYYI
336
DMQKF
341
PLRMK
346
DNDLL
351
VTELY
356
HDPSN
361
DAITA
366
LSVYL
371
TPKTS
376
VSGNW
381
IEIAY
386
GTSSG
391
AVRVI
396
VQHPE
401
TVGSG
406
PQLFQ
411
TFTVH
416
RSPVT
421
KIMLS
426
EKHLV
431
SVCAD
436
NNHVR
441
TWTVT
446
RFRGM
451
ISTQP
456
GSTPL
461
ASFKI
466
LSLEE
471
TESHG
476
SYSSG
481
NDIGP
486
FGERD
491
DQQVF
496
IQKVV
501
PITNK
506
LFVRL
511
SSTGK
516
RICEI
521
QAVDC
526
TTISS
531
FTVRE
536
CEGSS
541
RMGSR
546
PRRYL
551
FTGHT
556
NGSIQ
561
MWDLT
566
TAMDM
571
VNKSE
576
DKDVG
581
GPTEE
586
ELLKL
591
LDQCD
596
LSTSR
601
CATPN
606
ISPAT
611
SVVQH
616
SHLRE
621
SNSSL
626
QLQHH
631
DTTHE
636
AATYG
641
SMRPY
646
RESPL
651
LARAR
656
RTESF
661
HSYRD
666
FQTIN
671
LNRNV
676
ERAVP
681
ENGNL
686
GPIQA
691
EVKGA
696
TGECN
701
ISERK
706
SPGVE
711
IKSLR
716
ELDSG
721
LEVHK
726
IAEGF
731
SESKK
736
RSSED
741
ENENK
746
IEFRK
751
KGGFE
756
GGGFL
761
GRKKV
766
PYLAS
771
SPSTS
776
DGGTD
781
SPGTA
786
SPSPT
791
KTTPS
796
PRHKK
801
SDSSG
806
QEYSL
811
Mutation Information
DNA mutation:
None
Peptide Range:
575 ~ 599
Mut AA position:
587 (13 in Wild Type peptide)
Alignment
Wild Type:
"MVNKSEDKDVGGPTEEELLKLLDQC
||||||||||||.||||||||||||
Mutant:
MVNKSEDKDVGGATEEELLKLLDQC"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KCTD3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay