Immunogenicity 5832

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LIMCH1
Transcript ID
NM_014988
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (1083 aa)
MACPA
1
LGLEA
6
LQPLQ
11
PEPPP
16
EPAFS
21
EAQKW
26
IEQVT
31
GRSFG
36
DKDFR
41
TGLEN
46
GILLC
51
ELLNA
56
IKPGL
61
VKKIN
66
RLPTP
71
IAGLD
76
NIILF
81
LRGCK
86
ELGLK
91
ESQLF
96
DPSDL
101
QDTSN
106
RVTVK
111
SLDYS
116
RKLKN
121
VLVTI
126
YWLGK
131
AANSC
136
TSYSG
141
TTLNL
146
KEFEG
151
LLAQM
156
RKDTD
161
DIESP
166
KRSIR
171
DSGYI
176
DCWDS
181
ERSDS
186
LSPPR
191
HGRDD
196
SFDSL
201
DSFGS
206
RSRQT
211
PSPDV
216
VLRGS
221
SDGRG
226
SDSES
231
DLPHR
236
KLPDV
241
KKDDM
246
SARRT
251
SHGEP
256
KSAVP
261
FNQYL
266
PNKSN
271
QTAYV
276
PAPLR
281
KKKAE
286
REEYR
291
KSWST
296
ATSPL
301
GGERP
306
FRYGP
311
RTPVS
316
DDAES
321
TSMFD
326
MRCEE
331
EAAVQ
336
PHSRA
341
RQEQL
346
QLINN
351
QLREE
356
DDKWQ
361
DDLAR
366
WKSRR
371
RSVSQ
376
DLIKK
381
EEERK
386
KMEKL
391
LAGED
396
GTSER
401
RKSIK
406
TYREI
411
VQEKE
416
RRERE
421
LHEAY
426
KNARS
431
QEEAE
436
GILQQ
441
YIERF
446
TISEA
451
VLERL
456
EMPKI
461
LERSH
466
STEPN
471
LSSFL
476
NDPNP
481
MKYLR
486
QQSLP
491
PPKFT
496
ATVET
501
TIARA
506
SVLDT
511
SMSAG
516
SGSPS
521
KTVTP
526
KAVPM
531
LTPKP
536
YSQPK
541
NSQDV
546
LKTFK
551
VDGKV
556
SVNGE
561
TVHRE
566
EEKER
571
ECPTV
576
APAHS
581
LTKSQ
586
MFEGV
591
ARVHG
596
SPLEL
601
KQDNG
606
SIEIN
611
IKKPN
616
SVPQE
621
LAATT
626
EKTEP
631
NSQED
636
KNDGG
641
KSRKG
646
NIELA
651
SSEPQ
656
HFTTT
661
VTRCS
666
PTVAF
671
VEFPS
676
SPQLK
681
NDVSE
686
EKDQK
691
KPENE
696
MSGKV
701
ELVLS
706
QKVVK
711
PKSPE
716
PEATL
721
TFPFL
726
DKMPE
731
ANQLH
736
LPNLN
741
SQVDS
746
PSSEK
751
SPVMT
756
PQFKF
761
WAWDP
766
EEERR
771
RQEKW
776
QQEQE
781
RLLQE
786
RYQKE
791
QDKLK
796
EEWEK
801
AQKEV
806
EEEER
811
RYYEE
816
ERKII
821
EDTVV
826
PFTVS
831
SSSAD
836
QLSTS
841
SSMTE
846
GSGTM
851
NKIDL
856
GNCQD
861
EKQDR
866
RWKKS
871
FQGDD
876
SDLLL
881
KTRES
886
DRLEE
891
KGSLT
896
EGALA
901
HSGNP
906
VSKGV
911
HEDHQ
916
LDTEA
921
GAPHC
926
GTNPQ
931
LAQDP
936
SQNQQ
941
TSNPT
946
HSSED
951
VKPKT
956
LPLDK
961
SINHQ
966
IESPS
971
ERRKK
976
SPREH
981
FQAGP
986
FSPCS
991
PTPPG
996
QSPNR
1001
SISGK
1006
KLCSS
1011
CGLPL
1016
GKGAA
1021
MIIET
1026
LNLYF
1031
HIQCF
1036
RCGIC
1041
KGQLG
1046
DAVSG
1051
TDVRI
1056
RNGLL
1061
NCNDC
1066
YMRSR
1071
SAGQP
1076
TTL
1081
Mutation Information
DNA mutation:
None
Peptide Range:
987 ~ 1011
Mut AA position:
999 (13 in Wild Type peptide)
Alignment
Wild Type:
"QAGPFSPCSPTPPGQSPNRSISGKK
||||||||||||.||||||||||||
Mutant:
QAGPFSPCSPTPHGQSPNRSISGKK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LIMCH1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay