Immunogenicity 5838

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CEL
Transcript ID
NM_004460
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (760 aa)
MKTWV
1
KIVFG
6
VATSA
11
VLALL
16
VMCIV
21
LRPSR
26
VHNSE
31
ENTMR
36
ALTLK
41
DILNG
46
TFSYK
51
TFFPN
56
WISGQ
61
EYLHQ
66
SADNN
71
IVLYN
76
IETGQ
81
SYTIL
86
SNRTM
91
KSVNA
96
SNYGL
101
SPDRQ
106
FVYLE
111
SDYSK
116
LWRYS
121
YTATY
126
YIYDL
131
SNGEF
136
VRGNE
141
LPRPI
146
QYLCW
151
SPVGS
156
KLAYV
161
YQNNI
166
YLKQR
171
PGDPP
176
FQITF
181
NGREN
186
KIFNG
191
IPDWV
196
YEEEM
201
LATKY
206
ALWWS
211
PNGKF
216
LAYAE
221
FNDTD
226
IPVIA
231
YSYYG
236
DEQYP
241
RTINI
246
PYPKA
251
GAKNP
256
VVRIF
261
IIDTT
266
YPAYV
271
GPQEV
276
PVPAM
281
IASSD
286
YYFSW
291
LTWVT
296
DERVC
301
LQWLK
306
RVQNV
311
SVLSI
316
CDFRE
321
DWQTW
326
DCPKT
331
QEHIE
336
ESRTG
341
WAGGF
346
FVSTP
351
VFSYD
356
AISYY
361
KIFSD
366
KDGYK
371
HIHYI
376
KDTVE
381
NAIQI
386
TSGKW
391
EAINI
396
FRVTQ
401
DSLFY
406
SSNEF
411
EEYPG
416
RRNIY
421
RISIG
426
SYPPS
431
KKCVT
436
CHLRK
441
ERCQY
446
YTASF
451
SDYAK
456
YYALV
461
CYGPG
466
IPIST
471
LHDGR
476
TDQEI
481
KILEE
486
NKELE
491
NALKN
496
IQLPK
501
EEIKK
506
LEVDE
511
ITLWY
516
KMILP
521
PQFDR
526
SKKYP
531
LLIQV
536
YGGPC
541
SQSVR
546
SVFAV
551
NWISY
556
LASKE
561
GMVIA
566
LVDGR
571
GTAFQ
576
GDKLL
581
YAVYR
586
KLGVY
591
EVEDQ
596
ITAVR
601
KFIEM
606
GFIDE
611
KRIAI
616
WGWSY
621
GGYVS
626
SLALA
631
SGTGL
636
FKCGI
641
AVAPV
646
SSWEY
651
YASVY
656
TERFM
661
GLPTK
666
DDNLE
671
HYKNS
676
TVMAR
681
AEYFR
686
NVDYL
691
LIHGT
696
ADDNV
701
HFQNS
706
AQIAK
711
ALVNA
716
QVDFQ
721
AMWYS
726
DQNHG
731
LSGLS
736
TNHLY
741
THMTH
746
FLKQC
751
FSLSD
756
Mutation Information
DNA mutation:
None
Peptide Range:
172 ~ 196
Mut AA position:
184 (13 in Wild Type peptide)
Alignment
Wild Type:
"LKQRPGDPPFQITFNGRENKIFNGI
||||||||||||.||||||||||||
Mutant:
LKQRPGDPPFQIIFNGRENKIFNGI"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FAP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay