Immunogenicity 5844

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
FAM47A
Transcript ID
NM_203408
HLA INFO
A*29:02
TCR INFO

No TCR info found!

T cell Tumor cell A*29:02
sequence
Full length protein sequence (791 aa)
MGDQR
1
LQDWL
6
RSPGM
11
DSKPW
16
YCNKR
21
PSKCF
26
AKCKH
31
RRLRF
36
PPMDT
41
QNWVF
46
VKEGM
51
DDFRY
56
GCPSP
61
EDTLV
66
CRRDE
71
FLLPK
76
ISLRG
81
PQADP
86
KSGQK
91
KLLKK
96
AALFS
101
KLSPA
106
QLARK
111
AFVEQ
116
VEAQL
121
MAKHP
126
LAMYP
131
NLGED
136
MPPDL
141
LLQVL
146
KHLDP
151
ERELE
156
DAWAC
161
CETQE
166
KTTEV
171
PTEPG
176
KHPCG
181
EFCLK
186
PPETP
191
VSHLL
196
PEPPE
201
TGVSH
206
LSPEP
211
PKTPV
216
SSLRP
221
EPPET
226
GVSHL
231
RPEPP
236
ETGVS
241
HIRPG
246
PPITR
251
RRSSL
256
LRQLL
261
KLDSE
266
RKLED
271
ARAPC
276
EGREK
281
TTDEP
286
TEPGK
291
YPCGK
296
FCPRP
301
FETPL
306
SHLRQ
311
EPPKT
316
PVSSL
321
RPEPP
326
ETGES
331
HLRLE
336
HSKTR
341
RGSSL
346
RSEPS
351
ETGVS
356
RLRLA
361
PPKTR
366
RGSSL
371
HAEPS
376
KTGVS
381
HLSPE
386
PPKTE
391
VSHLH
396
PVPPK
401
TGVCH
406
LRLEP
411
PDTSQ
416
VSNLL
421
LYILK
426
VLDSG
431
RTLKD
436
VWDRC
441
EARVK
446
KTKEP
451
TEPHK
456
SPCGE
461
PCLQP
466
PETQV
471
SHPHP
476
EHPKT
481
RRRSS
486
LHSQP
491
PKTRR
496
TSSLR
501
SEPPK
506
TRRTS
511
SLRSE
516
PPKTR
521
RTSSL
526
GPEPP
531
KTRRV
536
SSLRP
541
ELPKS
546
RRVSS
551
LHPEP
556
PKAPE
561
SHQFS
566
EPPKI
571
RASYI
576
KELLQ
581
EDTPS
586
TKECV
591
SDSLQ
596
YRYTS
601
EKLRE
606
FFKWA
611
GDLGA
616
DEESI
621
RNLFD
626
FTPKY
631
RATHE
636
DQKFK
641
KVKEC
646
SSELK
651
YSMEL
656
DEKDE
661
DKFFS
666
QEKYW
671
GRKFH
676
TPSNS
681
YTAQR
686
VKMKY
691
GAWYL
696
KPKLW
701
KKLRS
706
DEPLI
711
DPKLL
716
LKKPD
721
EPDVL
726
DDLYG
731
PIAFK
736
DFILS
741
KGYEM
746
PGIIQ
751
RLFAR
756
RGWTY
761
DSVKT
766
PIQRA
771
MIFYK
776
YKEIV
781
EASEE
786
D
791
Mutation Information
DNA mutation:
None
Peptide Range:
334 ~ 358
Mut AA position:
346 (13 in Wild Type peptide)
Alignment
Wild Type:
"ESHLRLEHSKTRRGSSLRSEPSETG
||||||||||||.||||||||||||
Mutant:
ESHLRLEHSKTRQGSSLRSEPSETG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FAM47A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay