Immunogenicity 5881

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FAM47C
Transcript ID
NM_001013736
HLA INFO
DQA*02:01 / DQB*02:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:01
sequence
Full length protein sequence (1035 aa)
MGDQR
1
PQDRP
6
SSPGM
11
DSTPW
16
YCDKP
21
PSKYF
26
AKRKH
31
RRLRF
36
PPVDT
41
QNWVF
46
VTEGM
51
DDFRY
56
GCQSP
61
EDTLV
66
CRRDE
71
FLLPK
76
ISLRG
81
PQADP
86
KSRKK
91
KLLKK
96
AALFS
101
KLSPA
106
QPARK
111
AFVEE
116
VEAQL
121
MTKHP
126
LAMYP
131
NLGED
136
MPPDL
141
LLQVL
146
KPLDP
151
ERKLE
156
DAGSC
161
EGQEK
166
TTDEP
171
TEPGK
176
YPCGE
181
FSPRP
186
PETRV
191
SCLPP
196
EPPKT
201
PVSSL
206
RPEPP
211
ETGVS
216
HLRPQ
221
PPKTQ
226
VSSLH
231
LEPPE
236
TGVSH
241
LRPEP
246
PKTQV
251
SSLHL
256
EPPET
261
GVSHL
266
YLEPP
271
GTGVS
276
HLCPE
281
PPKTR
286
VSHLH
291
REPPE
296
TGVPD
301
LCLEP
306
PKSRV
311
SHLRP
316
EPSET
321
GVSHL
326
HPEPP
331
KTLVS
336
SLHPE
341
PPETG
346
VSHLC
351
PEPPE
356
TRVSP
361
LRQLP
366
PEAGV
371
SHLCP
376
EPPKT
381
RVPPL
386
RPETP
391
KNGVS
396
PLFPE
401
PPKTR
406
ISNLR
411
SEPPK
416
IGVSH
421
LCLEP
426
PKTRG
431
SHLRP
436
EPPET
441
GVSHL
446
RPEPP
451
KTRVS
456
SLHLE
461
PPETG
466
VSHLC
471
PEPPE
476
KDVSH
481
LRPEP
486
PDTGV
491
SHLCP
496
EPPKT
501
RVSHL
506
RPEPS
511
ETGVS
516
HLRPE
521
PPKIL
526
VSSLH
531
QAPPE
536
SSVSH
541
LRPEP
546
PETGV
551
SHLRP
556
EPPKT
561
RMYSL
566
RPEPP
571
DTGVS
576
HLCPE
581
PPKTR
586
VSSLP
591
PEPPE
596
TGVSH
601
LCPEP
606
PETRV
611
SHLRP
616
EPPET
621
GVSHL
626
RPEPP
631
KTRMY
636
SLRPE
641
PPNTG
646
VSHLC
651
PEPPK
656
TRVSS
661
LPPEP
666
PETGV
671
SHLCP
676
EPPET
681
RVSHL
686
RPEPP
691
ETGVS
696
RLHPE
701
PPKTR
706
VSSLH
711
AEPPE
716
SRVSH
721
LCPEP
726
PETGV
731
SHLRP
736
EPPKP
741
RVSSL
746
RPEPL
751
ETRVS
756
HLRPE
761
PPETG
766
VSHLH
771
PELPK
776
PRVSS
781
LHLEP
786
PKTRR
791
VSSLR
796
LEPPK
801
TGRVS
806
SLCPE
811
PTKTG
816
ASHLK
821
ELFQE
826
GTSST
831
MECVS
836
DSLQR
841
RHTSR
846
KLRDF
851
KWAGD
856
LGVNE
861
ESISS
866
LFDFT
871
PECRA
876
TYQDQ
881
KNKKA
886
NECSS
891
GLKYS
896
MELDE
901
MDEVK
906
FFSQE
911
KDLDG
916
KIQNA
921
PNSHS
926
AQHVK
931
MGYGA
936
WYLKP
941
KLGKK
946
LRSDE
951
PLIDP
956
KLVLE
961
KPDEP
966
DILDG
971
LYGPI
976
AFKDF
981
ILSKG
986
YEMPG
991
IIQRL
996
FARRG
1001
WTYDS
1006
VKTPI
1011
QRAMQ
1016
VYKYK
1021
EDVTD
1026
ASEED
1031
Mutation Information
DNA mutation:
None
Peptide Range:
307 ~ 331
Mut AA position:
319 (13 in Wild Type peptide)
Alignment
Wild Type:
"CLEPPKSRVSHLRPEPSETGVSHLH
||||||||||||.||||||||||||
Mutant:
CLEPPKSRVSHLHPEPSETGVSHLH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FAM47C

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay