Immunogenicity 5887
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LRRC15
Transcript ID
NM_001135057
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (587 aa)
MPLDK
1
AMPLK
6
HYLLL
11
LVGCQ
16
AWGAG
21
LAYHG
26
CPSEC
31
TCSRA
36
SQVEC
41
TGARI
46
VAVPT
51
PLPWN
56
AMSLQ
61
ILNTH
66
ITELN
71
ESPFL
76
NISAL
81
IALRI
86
EKNEL
91
SRITP
96
GAFRN
101
LGSLR
106
YLSLA
111
NNKLQ
116
VLPIG
121
LFQGL
126
DSLES
131
LLLSS
136
NQLLQ
141
IQPAH
146
FSQCS
151
NLKEL
156
QLHGN
161
HLEYI
166
PDGAF
171
DHLVG
176
LTKLN
181
LGKNS
186
LTHIS
191
PRVFQ
196
HLGNL
201
QVLRL
206
YENRL
211
TDIPM
216
GTFDG
221
LVNLQ
226
ELALQ
231
QNQIG
236
LLSPG
241
LFHNN
246
HNLQR
251
LYLSN
256
NHISQ
261
LPPSV
266
FMQLP
271
QLNRL
276
TLFGN
281
SLKEL
286
SPGIF
291
GPMPN
296
LRELW
301
LYDNH
306
ISSLP
311
DNVFS
316
NLRQL
321
QVLIL
326
SRNQI
331
SFISP
336
GAFNG
341
LTELR
346
ELSLH
351
TNALQ
356
DLDGN
361
VFRML
366
ANLQN
371
ISLQN
376
NRLRQ
381
LPGNI
386
FANVN
391
GLMAI
396
QLQNN
401
QLENL
406
PLGIF
411
DHLGK
416
LCELR
421
LYDNP
426
WRCDS
431
DILPL
436
RNWLL
441
LNQPR
446
LGTDT
451
VPVCF
456
SPANV
461
RGQSL
466
IIINV
471
NVAVP
476
SVHVP
481
EVPSY
486
PETPW
491
YPDTP
496
SYPDT
501
TSVSS
506
TTELT
511
SPVED
516
YTDLT
521
TIQVT
526
DDRSV
531
WGMTQ
536
AQSGL
541
AIAAI
546
VIGIV
551
ALACS
556
LAACV
561
GCCCC
566
KKRSQ
571
AVLMQ
576
MKAPN
581
EC
586
Mutation Information
DNA mutation:
None
Peptide Range:
370 ~ 394
Mut AA position:
382 (13 in Wild Type peptide)
Alignment
Wild Type:
"LANLQNISLQNNRLRQLPGNIFANV
||||||||||||.||||||||||||
Mutant:
LANLQNISLQNNCLRQLPGNIFANV"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) LRRC15
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay