Immunogenicity 5900

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PRRT4
Transcript ID
NM_001174164
HLA INFO
B*18:01
TCR INFO

No TCR info found!

T cell Tumor cell B*18:01
sequence
Full length protein sequence (899 aa)
MARHG
1
CLGLG
6
LFCCV
11
LFAAT
16
VGPQP
21
TPSIP
26
GAPAT
31
TLTPV
36
PQSEA
41
SMLSL
46
NLGLN
51
FKFHL
56
RGPAA
61
VWGSP
66
VTETQ
71
PLSLG
76
PGQEP
81
GEEVA
86
SGLRT
91
DPLWE
96
LLVGS
101
SGNSL
106
TEWGS
111
TEGGS
116
KPRAS
121
SLLPE
126
STSRR
131
SGPSD
136
GPTAP
141
YQPRR
146
STVTW
151
DTALM
156
VTALP
161
SSAPR
166
PHQSE
171
LELKF
176
DMALR
181
AGAAP
186
TLGHR
191
TLPLL
196
PSLRA
201
SLAEI
206
AGRLG
211
PFGFF
216
GTTLS
221
PLRNF
226
SGLSP
231
PGETT
236
STSSA
241
SGVSG
246
SLGFL
251
GTTLS
256
LPPYS
261
LERKL
266
SSPSP
271
LDPAA
276
SLSFA
281
SIATT
286
SLDPT
291
VPISG
296
PDDLS
301
PPASL
306
GNPSG
311
QPECG
316
PGSCS
321
VGELP
326
EREGQ
331
PPEAP
336
RPLFF
341
LTLEA
346
DWAEA
351
RARWG
356
LAWEA
361
HVYGV
366
GALFG
371
LVALL
376
ALLAL
381
ALLPW
386
RCPPG
391
APCLA
396
LLDLL
401
LLSAG
406
TTRAF
411
PLFYD
416
AYGHR
421
DRLPA
426
LAWLL
431
LQDLP
436
LPCLA
441
AGLGL
446
ACLLL
451
ARPRP
456
PRCPT
461
GLAAL
466
LLLGL
471
GLAAA
476
AALGS
481
AAHRP
486
LRPLR
491
LASRG
496
LHAFL
501
AAFLS
506
GLLLA
511
LSCWG
516
GRRRR
521
AGAPL
526
GGSGF
531
KGATP
536
LPQGR
541
SPFAP
546
RESWR
551
RAART
556
APVAG
561
TFGLL
566
SGALQ
571
GYEVL
576
HALGY
581
GGQSG
586
LEGPW
591
PWWAF
596
QLGLR
601
LGEVG
606
VALPL
611
ALLGL
616
YPALC
621
SPRVP
626
PRCWA
631
KLFRL
636
SPGHA
641
APLLP
646
GGWVT
651
GPPDK
656
EPLGS
661
AIARG
666
DAELL
671
QLCAL
676
AGPGP
681
DLLLQ
686
GGGCR
691
GFEGA
696
AANPA
701
PSPAS
706
SPCSD
711
YTVDF
716
RPPSP
721
INLRR
726
SIEEA
731
LCSEA
736
LLAPG
741
LFQGP
746
AFEDA
751
LPGLG
756
LYRTA
761
SLGTG
766
GRASE
771
RSGEA
776
SGPAA
781
PPELP
786
SPGAW
791
PAGSS
796
VSSGS
801
FCGLS
806
RDSSS
811
MLLCS
816
SPDRP
821
PRCPL
826
VCVLS
831
PPRPS
836
GSSPS
841
LPASG
846
SYQAL
851
SPPSR
856
DSPEP
861
ASELQ
866
AEEAL
871
LQEQF
876
LDACR
881
QIDEL
886
SVGSD
891
TIDL
896
Mutation Information
DNA mutation:
None
Peptide Range:
540 ~ 564
Mut AA position:
552 (13 in Wild Type peptide)
Alignment
Wild Type:
"PLPQGRSPFAPRESWRRAARTAPVA
||||||||||||.||||||||||||
Mutant:
PLPQGRSPFAPRGSWRRAARTAPVA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRRT4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay