Immunogenicity 5905

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PLD6
Transcript ID
NM_178836
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (252 aa)
MGRLS
1
WQVAA
6
AAAVG
11
LALTL
16
EALPW
21
VLRWL
26
RSRRR
31
RPRRE
36
ALFFP
41
SQVTC
46
TEALL
51
RAPGA
56
ELAEL
61
PEGCP
66
CGLPH
71
GESAL
76
SRLLR
81
ALLAA
86
RASLD
91
LCLFA
96
FSSPQ
101
LGRAV
106
QLLHQ
111
RGVRV
116
RVVTD
121
CDYMA
126
LNGSQ
131
IGLLR
136
KAGIQ
141
VRHDQ
146
DPGYM
151
HHKFA
156
IVDKR
161
VLITG
166
SLNWT
171
TQAIQ
176
NNREN
181
VLITE
186
DDEYV
191
RLFLE
196
EFERI
201
WEQFN
206
PTKYT
211
FFPPK
216
KSHGS
221
CAPPV
226
SRAGG
231
RLLSW
236
HRTCG
241
TSSES
246
QT
251
Mutation Information
DNA mutation:
None
Peptide Range:
125 ~ 149
Mut AA position:
137 (13 in Wild Type peptide)
Alignment
Wild Type:
"DCDYMALNGSQIGLLRKAGIQVRHD
||||||||||||.||||||||||||
Mutant:
DCDYMALNGSQIRLLRKAGIQVRHD"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PLD6

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay