Immunogenicity 5918

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF615
Transcript ID
NM_001199324
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (742 aa)
MMQAQ
1
ESLTL
6
EDVAV
11
DFTWE
16
EWQFL
21
SPAQK
26
DLYRD
31
VMLEN
36
YSNLV
41
AVGYQ
46
ASKPD
51
ALSKL
56
ERGEE
61
TCTTE
66
DEIYS
71
RICSD
76
SGGAS
81
GGAYA
86
EIRKI
91
DDPLQ
96
HHLQN
101
QSIQK
106
SVKQC
111
HEQNM
116
FGNIV
121
NQNKG
126
HFLLK
131
QDCDT
136
FDLHE
141
KPLKS
146
NLSFE
151
NQKRS
156
SGLKN
161
SAEFN
166
RDGKS
171
LFHAN
176
HKQFY
181
TEMKF
186
PAIAK
191
PINKS
196
QFIKQ
201
QRTHN
206
IENAH
211
VCSEC
216
GKAFL
221
KLSQF
226
IDHQR
231
VHTGE
236
KPHVC
241
SMCGK
246
AFSRK
251
SRLMD
256
HQRTH
261
TELKH
266
YECTE
271
CDKTF
276
LKKSQ
281
LNIHQ
286
KTHMG
291
GKPYT
296
CSQCG
301
KAFIK
306
KCRLI
311
YHQRT
316
HTGEK
321
PHGCS
326
VCGKA
331
FSTKF
336
SLTTH
341
QKTHT
346
GEKPY
351
ICSEC
356
GKGFI
361
EKRRL
366
TAHHR
371
THTGE
376
KPFIC
381
NKCGK
386
GFTLK
391
NSLIT
396
HQQTH
401
TGEKL
406
YTCSE
411
CGKGF
416
SMKHC
421
LMVHQ
426
RTHTG
431
EKPYK
436
CNECG
441
KGFAL
446
KSPLI
451
RHQRT
456
HTGEK
461
PYVCT
466
ECRKG
471
FTMKS
476
DLIVH
481
QRTHT
486
AEKPY
491
ICNDC
496
GKGFT
501
VKSRL
506
IVHQR
511
THTGE
516
KPYVC
521
GECGK
526
GFPAK
531
IRLMG
536
HQRTH
541
TGEKP
546
YICNE
551
CGKGF
556
TEKSH
561
LNVHR
566
RTHTG
571
EKPYV
576
CSECG
581
KGLTG
586
KSMLI
591
AHQRT
596
HTGEK
601
PYICN
606
ECGKG
611
FTMKS
616
TLSIH
621
QQTHT
626
GEKPY
631
KCNEC
636
DKTFR
641
KKTCL
646
IQHQR
651
FHTGK
656
TSFAC
661
TECGK
666
FSLRK
671
NDLIT
676
HQRIH
681
TGEKP
686
YKCSD
691
CGKAF
696
TTKSG
701
LNVHQ
706
RKHTG
711
ERPYG
716
CSDCG
721
KAFAH
726
LSILV
731
KHRRI
736
HR
741
Mutation Information
DNA mutation:
None
Peptide Range:
307 ~ 331
Mut AA position:
319 (13 in Wild Type peptide)
Alignment
Wild Type:
"AFIKKCRLIYHQRTHTGEKPHGCSV
||||||||||||.||||||||||||
Mutant:
AFIKKCRLIYHQQTHTGEKPHGCSV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF615

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay