Immunogenicity 5932

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
ZNF519
Transcript ID
NM_145287
HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:01
sequence
Full length protein sequence (540 aa)
MELLT
1
FRDVA
6
IEFSP
11
EEWKC
16
LDPAQ
21
QNLYR
26
DVMLE
31
NYRNL
36
VSLAV
41
YSYYN
46
QGILP
51
EQGIQ
56
DSFKK
61
ATLGR
66
YGSCG
71
LENIC
76
LWKNW
81
ESIGE
86
GEGQK
91
ECYNL
96
CSQYL
101
TTSHN
106
KHLTV
111
KGDKE
116
YRIFQ
121
KKPQF
126
LSAAP
131
TEPCI
136
PMNKY
141
QHKFL
146
KSVFC
151
NKNQI
156
NFNHD
161
SNISK
166
HHSTH
171
FLENY
176
YNCNE
181
CEKVF
186
YQSSK
191
LIFPE
196
NIHIQ
201
KKPYN
206
SNECG
211
ETSDP
216
FSKLT
221
QHQRI
226
YIGES
231
SQRCN
236
KKCII
241
VFSQS
246
HLKGH
251
KIINT
256
GEKSV
261
KYKER
266
GKAFT
271
RGLHL
276
GHQKI
281
HTGEK
286
PYKCK
291
KCDKA
296
FNKSS
301
HLAQH
306
QRIHT
311
GEKPF
316
KCKEC
321
GKAFN
326
RGSYL
331
TQHQR
336
IHTGE
341
RAFKC
346
EECGK
351
AFNRG
356
SYLTQ
361
HQRIH
366
TGEKP
371
FRCKE
376
CGKAF
381
NRSSY
386
VTQHQ
391
RMHTG
396
EKPFK
401
CKECG
406
KAFNR
411
ASHLT
416
QHQRI
421
HTGEK
426
HFKCK
431
ECGKA
436
FNRGS
441
HLTRH
446
QRIHT
451
GEKSF
456
KCEEC
461
GKAFI
466
WGSHL
471
TQHQR
476
VHTGE
481
KFFKC
486
KECGK
491
AFTRS
496
SHLTQ
501
HQRIH
506
TGEKP
511
FKCKE
516
CGKAF
521
NRRST
526
LTQHQ
531
IIHTR
536
Mutation Information
DNA mutation:
None
Peptide Range:
496 ~ 520
Mut AA position:
508 (13 in Wild Type peptide)
Alignment
Wild Type:
"AFTRSSHLTQHQRIHTGEKPFKCKE
||||||||||||.||||||||||||
Mutant:
AFTRSSHLTQHQIIHTGEKPFKCKE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF519

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay