Immunogenicity 5963

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
RPS6KL1
Transcript ID
NM_031464
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (549 aa)
MSLVA
1
CECLP
6
SPGLE
11
PEPCS
16
RARSQ
21
AHVYL
26
EQIRN
31
RVALG
36
VPDMT
41
KRDYL
46
VDAAT
51
QIRLA
56
LERDV
61
SEDYE
66
AAFNH
71
YQNGV
76
DVLLR
81
GIHVD
86
PNKER
91
REAVK
96
LKITK
101
YLRRA
106
EEIFN
111
CHLQR
116
PLSSG
121
ASPSA
126
GFSSL
131
RLRPI
136
RTLSS
141
AVEQL
146
RGCRV
151
VGVIE
156
KVQLV
161
QDPAT
166
GGTFV
171
VKSLP
176
RCHMV
181
SRERL
186
TIIPH
191
GVPYM
196
TKLLR
201
YFVSE
206
DSIFL
211
HLEHV
216
QGGTL
221
WSHLL
226
SQAHS
231
RHSGL
236
SSGST
241
QERMK
246
AQLNP
251
HLNLL
256
TPARL
261
PSGHA
266
PGQDR
271
IALEP
276
PRTSP
281
NLLLA
286
GEAPS
291
TRPQR
296
EAEGE
301
PTART
306
STSGS
311
SDLPK
316
APGGH
321
LHLQA
326
RRAGQ
331
NSDAG
336
PPRGL
341
TWVPE
346
GAGPV
351
LGGCG
356
RGMDQ
361
SCLSA
366
DGAGR
371
GCGRA
376
TWSVR
381
EEQVK
386
QWAAE
391
MLVAL
396
EALHE
401
QGVLC
406
RDLHP
411
GNLLL
416
DQAGH
421
IRLTY
426
FGQWS
431
EVEPQ
436
CCGEA
441
VDNLY
446
SAPEV
451
GGISE
456
LTEAC
461
DWWSF
466
GSLLY
471
ELLTG
476
MALSQ
481
SHPSG
486
IQAHT
491
QLQLP
496
EWLSR
501
PAASL
506
LTELL
511
QFEPT
516
RRLGM
521
GEGGV
526
SKLKS
531
HPFFS
536
TIQWS
541
KLVG
546
Mutation Information
DNA mutation:
None
Peptide Range:
22 ~ 46
Mut AA position:
34 (13 in Wild Type peptide)
Alignment
Wild Type:
"ARSQAHVYLEQIRNRVALGVPDMTK
||||||||||||.||||||||||||
Mutant:
ARSQAHVYLEQIHNRVALGVPDMTK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RPS6KL1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay