Immunogenicity 6047
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PRAMEF7
Transcript ID
NM_001012277
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (474 aa)
MSIRA
1
PPRLL
6
ELARQ
11
RLLRD
16
QALAI
21
STMEE
26
LPREL
31
FPTLF
36
MEAFS
41
RRRCE
46
TLKTM
51
VQAWP
56
FTRLP
61
LGSLM
66
KSPHL
71
ESLKS
76
VLEGV
81
DVLLT
86
QEVRP
91
RQSKL
96
QVLDL
101
RNVDE
106
NFCDI
111
FSGAT
116
ASFPE
121
ALSQK
126
QTADN
131
CPGTG
136
RQQPF
141
MVFID
146
LCLKN
151
RTLDE
156
CLTHL
161
LEWGK
166
QRKGL
171
LHVCC
176
KELQV
181
FGMPI
186
HSIIE
191
VLNMV
196
ELDCI
201
QEVEV
206
CCPWE
211
LSTLV
216
KFAPY
221
LGQMR
226
NLRKL
231
VLFNI
236
RASAC
241
IPPDN
246
KGQFI
251
ARFTS
256
QFLKL
261
DYFQN
266
LSMHS
271
VSFLE
276
GHLDQ
281
LLRCL
286
QASLE
291
MVVMT
296
DCLLS
301
ESDLK
306
HLSWC
311
PSIRQ
316
LKELD
321
LRGVT
326
LTHFS
331
PEPLT
336
GLLEQ
341
AVATL
346
QTLDL
351
EDCGI
356
MDSQL
361
SAILP
366
VLSRC
371
SQLST
376
FSFCG
381
NLISM
386
AALEN
391
LLRHT
396
VGLSK
401
LSLEL
406
YPAPL
411
ESYDT
416
QGALC
421
WGRFA
426
ELGAE
431
LMNTL
436
RDLRQ
441
PKIIV
446
FCTVP
451
CPRCG
456
IRASY
461
DLEPS
466
HCLC
471
Mutation Information
DNA mutation:
None
Peptide Range:
281 ~ 305
Mut AA position:
293 (13 in Wild Type peptide)
Alignment
Wild Type:
"GHLDQLLRCLQASLEMVVMTDCLLS
||||||||||||.||||||||||||
Mutant:
GHLDQLLRCLQAPLEMVVMTDCLLS"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PRAMEF7
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay