Immunogenicity 6068
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PRAMEF1
Transcript ID
NM_023013
HLA INFO
A*25:01
TCR INFO
No TCR info found!
Full length protein sequence (474 aa)
MSIQA
1
PPRLL
6
ELAGQ
11
SLLRD
16
QALSI
21
SAMEE
26
LPRVL
31
YLPLF
36
MEAFS
41
RRHFQ
46
TLTVM
51
VQAWP
56
FTCLP
61
LGSLM
66
KTLHL
71
ETLKA
76
LLEGL
81
HMLLT
86
QKDRP
91
RRWKL
96
QVLDL
101
RDVDE
106
NFWAR
111
WPGAW
116
ALSCF
121
PETTS
126
KRQTA
131
EDCPR
136
MGEHQ
141
PLKVF
146
IDICL
151
KEIPQ
156
DECLR
161
YLFQW
166
VYQRR
171
GLVHL
176
CCSKL
181
VNYLT
186
PIKYL
191
RKSLK
196
IIYLN
201
SIQEL
206
EIRNM
211
SWPRL
216
IRKLR
221
CYLKE
226
MKNLR
231
KLVFS
236
RCHHY
241
TSDNE
246
LEGRL
251
VAKFS
256
SVFLR
261
LEHLQ
266
LLKIK
271
LITFF
276
SGHLE
281
QLIRC
286
LQNPL
291
ENLEL
296
TYGYL
301
LEEDM
306
KCLSQ
311
YPSLG
316
YLKHL
321
NLSYV
326
LLFRI
331
SLEPL
336
GALLE
341
KIAAS
346
LKTLI
351
LEGCQ
356
IHYSQ
361
LSAIL
366
PGLSR
371
CSQLT
376
TFYFG
381
RNCMS
386
IDALK
391
DLLRH
396
TSGLS
401
KLSLE
406
TYPAP
411
EESLN
416
SLVRV
421
NWEIF
426
TPLRA
431
ELMCT
436
LREVR
441
QPKRI
446
FIGPT
451
PCPSC
456
GSSPS
461
EELEL
466
HLCC
471
Mutation Information
DNA mutation:
None
Peptide Range:
40 ~ 64
Mut AA position:
52 (13 in Wild Type peptide)
Alignment
Wild Type:
"FMEAFSRRHFQTLTVMVQAWPFTCL
||||||||||||.||||||||||||
Mutant:
FMEAFSRRHFQTVTVMVQAWPFTCL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PRAMEF1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay