Immunogenicity 6078

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
FAM53A
Transcript ID
NM_001174070
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (398 aa)
MVTLI
1
TEKLQ
6
SQSLD
11
DLTCK
16
AEAGP
21
LQYSA
26
ETLNK
31
SGRLF
36
PLELN
41
DQSPW
46
KVFSG
51
GPPVR
56
SQAAT
61
GPDFS
66
FLPGL
71
SAAAH
76
TMGLQ
81
WQPQS
86
PRPGA
91
GLGAA
96
STVDP
101
SESTG
106
SSTAP
111
PTKRH
116
CRSLS
121
EPEEL
126
VRCRS
131
PWRPG
136
SSKVW
141
TPVSK
146
RRCDS
151
GGSAT
156
RQGSP
161
GAVLP
166
RSAVW
171
STGPT
176
SPATP
181
RPSSA
186
SGGFV
191
DSSEG
196
SAGSG
201
PLWCS
206
AESCL
211
PSTRR
216
RPSLS
221
QERLA
226
GAGTP
231
LPWAS
236
SSPTS
241
TPALG
246
GRRGL
251
LRCRS
256
QPCVL
261
SGKRS
266
RRKRR
271
REEDA
276
RWTRP
281
SLDFL
286
KMTQT
291
LKNSK
296
SLCSL
301
NYEDD
306
DEDDT
311
PVKTV
316
LSSPC
321
DSRGL
326
PGITM
331
PGCSQ
336
RGLRT
341
SPVHP
346
NLWAS
351
RESVT
356
SDGSR
361
RSSGD
366
PRDGD
371
SVGEE
376
GVFPR
381
ARWEL
386
DLEQI
391
ENN
396
Mutation Information
DNA mutation:
None
Peptide Range:
307 ~ 331
Mut AA position:
319 (13 in Wild Type peptide)
Alignment
Wild Type:
"YEDDDEDDTPVKTVLSSPCDSRGLP
||||||||||||.||||||||||||
Mutant:
YEDDDEDDTPVKMVLSSPCDSRGLP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FAM53A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay