Immunogenicity 6095

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF546
Transcript ID
NM_178544
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (836 aa)
MQVDP
1
PLHGP
6
PNDFL
11
IFQII
16
PLHSL
21
SIMPR
26
FLWIL
31
CFSME
36
ETQGE
41
LTSSC
46
GSKTM
51
ANVSL
56
AFRDV
61
SIDLS
66
QEEWE
71
CLDAV
76
QRDLY
81
KDVML
86
ENYSN
91
LVSLG
96
YTIPK
101
PDVIT
106
LLEQE
111
KEPWI
116
VMREG
121
TRNWF
126
TDLEY
131
KYITK
136
NLLSE
141
KNVCK
146
IYLSQ
151
LQTGE
156
KSKNT
161
IHEDT
166
IFRNG
171
LQCKH
176
EFERQ
181
ERHQM
186
GCVSQ
191
MLIQK
196
QISHP
201
LHPKI
206
HAREK
211
SYECK
216
ECRKA
221
FRQQS
226
YLIQH
231
LRIHT
236
GERPY
241
KCMEC
246
GKAFC
251
RVGDL
256
RVHHT
261
IHAGE
266
RPYEC
271
KECGK
276
AFRLH
281
YHLTE
286
HQRIH
291
SGVKP
296
YECKE
301
CGKAF
306
SRVRD
311
LRVHQ
316
TIHAG
321
ERPYE
326
CKECG
331
KAFRL
336
HYQLT
341
EHQRI
346
HTGER
351
PYECK
356
VCGKT
361
FRVQR
366
HISQH
371
QKIHT
376
GVKPY
381
KCNEC
386
GKAFS
391
HGSYL
396
VQHQK
401
IHTGE
406
KPYEC
411
KECGK
416
SFSFH
421
AELAR
426
HRRIH
431
TGEKP
436
YECRE
441
CGKAF
446
RLQTE
451
LTRHH
456
RTHTG
461
EKPYE
466
CKECG
471
KAFIC
476
GYQLT
481
LHLRT
486
HTGEI
491
PYECK
496
ECGKT
501
FSSRY
506
HLTQH
511
YRIHT
516
GEKPY
521
ICNEC
526
GKAFR
531
LQGEL
536
TRHHR
541
IHTCE
546
KPYEC
551
KECGK
556
AFIHS
561
NQFIS
566
HQRIH
571
TSEST
576
YICKE
581
CGKIF
586
SRRYN
591
LTQHF
596
KIHTG
601
EKPYI
606
CNECG
611
KAFRF
616
QTELT
621
QHHRI
626
HTGEK
631
PYKCT
636
ECGKA
641
FIRST
646
HLTQH
651
HRIHT
656
GEKPY
661
ECTEC
666
GKTFS
671
RHYHL
676
TQHHR
681
GHTGE
686
KPYIC
691
NECGN
696
AFICS
701
YRLTL
706
HQRIH
711
TGELP
716
YECKE
721
CGKTF
726
SRRYH
731
LTQHF
736
RLHTG
741
EKPYS
746
CKECG
751
NAFRL
756
QAELT
761
RHHIV
766
HTGEK
771
PYKCK
776
ECGKA
781
FSVNS
786
ELTRH
791
HRIHT
796
GEKPY
801
QCKEC
806
GKAFI
811
RSDQL
816
TLHQR
821
NHISE
826
EVLCI
831
M
836
Mutation Information
DNA mutation:
None
Peptide Range:
125 ~ 149
Mut AA position:
137 (13 in Wild Type peptide)
Alignment
Wild Type:
"GTRNWFTDLEYKYITKNLLSEKNVC
||||||||||||.||||||||||||
Mutant:
GTRNWFTDLEYKCITKNLLSEKNVC"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF546

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay