Immunogenicity 61
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
AP3D1
Transcript ID
uc031riw.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1203 aa)
MALKM
1
VKGSI
6
DRMFD
11
KNLQD
16
LVRGI
21
RNHKE
26
DEAKY
31
ISQCI
36
DEIKQ
41
ELKQD
46
NIAVK
51
ANAVC
56
KLTYL
61
QMLGY
66
DISWA
71
AFNII
76
EVMSA
81
SKFTF
86
KRIGY
91
LAASQ
96
SFHEG
101
TDVIM
106
LTTNQ
111
IRKDL
116
SSPSQ
121
YDTGV
126
ALTGL
131
SCFVT
136
PDLAR
141
DLAND
146
IMTLM
151
SHTKP
156
YIRKK
161
AVLIM
166
YKVFL
171
KYPES
176
LRPAF
181
PRLKE
186
KLEDP
191
DPGVQ
196
SAAVN
201
VICEL
206
ARRNP
211
KNYLS
216
LAPLF
221
FKLMT
226
SSTNN
231
WVLIK
236
IIKLF
241
GALTP
246
LEPRL
251
GKKLI
256
EPLTN
261
LIHST
266
SAMSL
271
LYECV
276
NTVIA
281
VLISL
286
SSGMP
291
NHSAS
296
IQLCV
301
QKLRI
306
LIEDS
311
DQNLK
316
YLGLL
321
AMSKI
326
LKTHP
331
KSVQS
336
HKDLI
341
LQCLD
346
DKDES
351
IRLRA
356
LDLLY
361
GMVSK
366
KNLME
371
IVKKL
376
MTHVD
381
KAEGT
386
TYRDE
391
LLTKI
396
IDICS
401
QSNYQ
406
YITNF
411
EWYIS
416
ILVEL
421
TRLEG
426
TRHGH
431
LIAAQ
436
MLDVA
441
IRVKA
446
IRKFA
451
VSQMS
456
ALLDS
461
AHLLA
466
SSTQR
471
NGICE
476
VLYAA
481
AWICG
486
EFSEH
491
LQEPH
496
HTLEA
501
MLRPR
506
VTTLP
511
GHIQA
516
VYVQN
521
VVKLY
526
ASILQ
531
QKEQA
536
GEAEG
541
AQAVT
546
QLMVD
551
RLPQF
556
VQSAD
561
LEVQE
566
RASCI
571
LQLVK
576
HIQKL
581
QAKDV
586
PVAEE
591
VSALF
596
AGELN
601
PVAPK
606
AQKKV
611
PVPEG
616
LDLDA
621
WINEP
626
LSDSE
631
SEDER
636
PRAVF
641
HEEEQ
646
RRPKH
651
RPSEA
656
DEEEL
661
ARRRE
666
ARKQE
671
QANNP
676
FYIKS
681
SPSPQ
686
KRYQD
691
TPGVE
696
HIPVV
701
QIDLS
706
VPLKV
711
PGLPM
716
SDQYV
721
KLEEE
726
RRHRQ
731
KLEKD
736
KRRKK
741
RKEKE
746
KKGKR
751
RHSSL
756
PTESD
761
EDIAP
766
AQQVD
771
IVTEE
776
MPENA
781
LPSDE
786
DDKDP
791
NDPYR
796
ALDID
801
LDKPL
806
ADSEK
811
LPIQK
816
HRNTE
821
TSKSP
826
EKDVP
831
MVEKK
836
SKKPK
841
KKEKK
846
HKEKE
851
RDKEK
856
KKEKE
861
KKAED
866
LDFWL
871
STTPP
876
PAPAP
881
APAPV
886
PSTDE
891
CEDAK
896
TEAQG
901
EEDDA
906
EGQDQ
911
DKKSP
916
KPKKK
921
KHRKE
926
KEERT
931
KGKKK
936
SKKQP
941
PGSEE
946
AAGEP
951
VQNGA
956
PEEEQ
961
LPPES
966
SYSLL
971
AENSY
976
VKMTC
981
DIRGS
986
LQEDS
991
QVTVA
996
IVLEN
1001
RSSSI
1006
LKGME
1011
LSVLD
1016
SLNAR
1021
MARPQ
1026
GSSVH
1031
DGVPV
1036
PFQLP
1041
PGVSN
1046
EAQYV
1051
FTIQS
1056
IVMAQ
1061
KLKGT
1066
LSFIA
1071
KNDEG
1076
ATHEK
1081
LDFRL
1086
HFSCS
1091
SYLIT
1096
TPCYS
1101
DAFAK
1106
LLESG
1111
DLSMS
1116
SIKVD
1121
GIRMS
1126
FQNLL
1131
AKICF
1136
HHHFS
1141
VVERV
1146
DSCAS
1151
MYSRS
1156
IQGHH
1161
VCLLV
1166
KKGEN
1171
SVSVD
1176
GKCSD
1181
STLLS
1186
NLLEE
1191
MKATL
1196
AKC
1201
Mutation Information
DNA mutation:
c.G1039A
Peptide Range:
607 ~ 631
Mut AA position:
619 (13 in Wild Type peptide)
Alignment
Wild Type:
"VAPKAQKKVPVPEGLDLDAWINEPL
||||||||||||.||||||||||||
Mutant:
VAPKAQKKVPVPKGLDLDAWINEPL"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) AP3D1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VAPKAQKKVPVPKGLDLDAWINEPL
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT