Immunogenicity 6110

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
C14orf180
Transcript ID
NM_001286399
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (177 aa)
MRTAA
1
GAVSP
6
DSRPE
11
TRRQT
16
RKNEE
21
AAWGP
26
RVCRA
31
EREDN
36
RKCPP
41
SILKR
46
SRPEH
51
HRPEA
56
KPQRT
61
SRRVW
66
FREPP
71
AVTVH
76
YIADK
81
NATAT
86
VRAVC
91
VRPAR
96
AGPGP
101
ILRPG
106
QARGN
111
GTGGP
116
AGPAP
121
RPCPA
126
PAARG
131
PHLLA
136
RPPAA
141
LTGRT
146
GRTGR
151
ASRRA
156
QALRG
161
LRDSL
166
SPGPA
171
AW
176
Mutation Information
DNA mutation:
None
Peptide Range:
87 ~ 111
Mut AA position:
99 (13 in Wild Type peptide)
Alignment
Wild Type:
"ATATVRAVCVRPARAGPGPILRPGQ
||||||||||||.||||||||||||
Mutant:
ATATVRAVCVRPTRAGPGPILRPGQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) C14orf180

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay