Immunogenicity 6120

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DDX4
Transcript ID
NM_024415
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (724 aa)
MGDED
1
WEAEI
6
NPHMS
11
SYVPI
16
FEKDR
21
YSGEN
26
GDNFN
31
RTPAS
36
SSEMD
41
DGPSR
46
RDHFM
51
KSGFA
56
SGRNF
61
GNRDA
66
GECNK
71
RDNTS
76
TMGGF
81
GVGKS
86
FGNRG
91
FSNSR
96
FEDGD
101
SSGFW
106
RESSN
111
DCEDN
116
PTRNR
121
GFSKR
126
GGYRD
131
GNNSE
136
ASGPY
141
RRGGR
146
GSFRG
151
CRGGF
156
GLGSP
161
NNDLD
166
PDECM
171
QRTGG
176
LFGSR
181
RPVLS
186
GTGNG
191
DTSQS
196
RSGSG
201
SERGG
206
YKGLN
211
EEVIT
216
GSGKN
221
SWKSE
226
AEGGE
231
SSDTQ
236
GPKVT
241
YIPPP
246
PPEDE
251
DSIFA
256
HYQTG
261
INFDK
266
YDTIL
271
VEVSG
276
HDAPP
281
AILTF
286
EEANL
291
CQTLN
296
NNIAK
301
AGYTK
306
LTPVQ
311
KYSIP
316
IILAG
321
RDLMA
326
CAQTG
331
SGKTA
336
AFLLP
341
ILAHM
346
MHDGI
351
TASRF
356
KELQE
361
PECII
366
VAPTR
371
ELVNQ
376
IYLEA
381
RKFSF
386
GTCVR
391
AVVIY
396
GGTQL
401
GHSIR
406
QIVQG
411
CNILC
416
ATPGR
421
LMDII
426
GKEKI
431
GLKQI
436
KYLVL
441
DEADR
446
MLDMG
451
FGPEM
456
KKLIS
461
CPGMP
466
SKEQR
471
QTLMF
476
SATFP
481
EEIQR
486
LAAEF
491
LKSNY
496
LFVAV
501
GQVGG
506
ACRDV
511
QQTVL
516
QVGQF
521
SKREK
526
LVEIL
531
RNIGD
536
ERTMV
541
FVETK
546
KKADF
551
IATFL
556
CQEKI
561
STTSI
566
HGDRE
571
QRERE
576
QALGD
581
FRFGK
586
CPVLV
591
ATSVA
596
ARGLD
601
IENVQ
606
HVINF
611
DLPST
616
IDEYV
621
HRIGR
626
TGRCG
631
NTGRA
636
ISFFD
641
LESDN
646
HLAQP
651
LVKVL
656
TDAQQ
661
DVPAW
666
LEEIA
671
FSTYI
676
PGFSG
681
STRGN
686
VFASV
691
DTRKG
696
KSTLN
701
TAGFS
706
SSQAP
711
NPVDD
716
ESWD
721
Mutation Information
DNA mutation:
None
Peptide Range:
618 ~ 642
Mut AA position:
630 (13 in Wild Type peptide)
Alignment
Wild Type:
"PSTIDEYVHRIGRTGRCGNTGRAIS
||||||||||||.||||||||||||
Mutant:
PSTIDEYVHRIGHTGRCGNTGRAIS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DDX4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay