Immunogenicity 6132

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
TRABD
Transcript ID
NM_025204
HLA INFO
B*18:01
TCR INFO

No TCR info found!

T cell Tumor cell B*18:01
sequence
Full length protein sequence (376 aa)
MDGEE
1
QQPPH
6
EANVE
11
PVVPS
16
EASEP
21
VPRVL
26
SGDPQ
31
NLSDV
36
DAFNL
41
LLEMK
46
LKRRR
51
QRPNL
56
PRTVT
61
QLVAE
66
DGSRV
71
YVVGT
76
AHFSD
81
DSKRD
86
VVKTI
91
REVQP
96
DVVVV
101
ELCQY
106
RVSML
111
KMDES
116
TLLRE
121
AQELS
126
LEKLQ
131
QAVRQ
136
NGLMS
141
GLMQM
146
LLLKV
151
SAHIT
156
EQLGM
161
APGGE
166
FREAF
171
KEASK
176
VPFCK
181
FHLGD
186
RPIPV
191
TFKRA
196
IAALS
201
FWQKV
206
RLAWG
211
LCFLS
216
DPISK
221
DDVER
226
CKQKD
231
LLEQM
236
MAEMI
241
GEFPD
246
LHRTI
251
VSERD
256
VYLTY
261
MLRQA
266
ARRLE
271
LPRAS
276
DAEPR
281
KCVPS
286
VVVGV
291
VGMGH
296
VPGIE
301
KNWST
306
DLNIQ
311
EIMTV
316
PPPSV
321
SGRVS
326
RLAVK
331
AAFFG
336
LLGYS
341
LYWMG
346
RRTAS
351
LVLSL
356
PAAQY
361
CLQRV
366
TEARH
371
K
376
Mutation Information
DNA mutation:
None
Peptide Range:
247 ~ 271
Mut AA position:
259 (13 in Wild Type peptide)
Alignment
Wild Type:
"EFPDLHRTIVSERDVYLTYMLRQAA
||||||||||||.||||||||||||
Mutant:
EFPDLHRTIVSECDVYLTYMLRQAA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TRABD

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay