Immunogenicity 6142

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
OAS3
Transcript ID
NM_006187
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (1087 aa)
MDLYS
1
TPAAA
6
LDRFV
11
ARRLQ
16
PRKEF
21
VEKAR
26
RALGA
31
LAAAL
36
RERGG
41
RLGAA
46
APRVL
51
KTVKG
56
GSSGR
61
GTALK
66
GGCDS
71
ELVIF
76
LDCFK
81
SYVDQ
86
RARRA
91
EILSE
96
MRASL
101
ESWWQ
106
NPVPG
111
LRLTF
116
PEQSV
121
PGALQ
126
FRLTS
131
VDLED
136
WMDVS
141
LVPAF
146
NVLGQ
151
AGSGV
156
KPKPQ
161
VYSTL
166
LNSGC
171
QGGEH
176
AACFT
181
ELRRN
186
FVNIR
191
PAKLK
196
NLILL
201
VKHWY
206
HQVCL
211
QGLWK
216
ETLPP
221
VYALE
226
LLTIF
231
AWEQG
236
CKKDA
241
FSLAE
246
GLRTV
251
LGLIQ
256
QHQHL
261
CVFWT
266
VNYGF
271
EDPAV
276
GQFLQ
281
RQLKR
286
PRPVI
291
LDPAD
296
PTWDL
301
GNGAA
306
WHWDL
311
LAQEA
316
ASCYD
321
HPCFL
326
RGMGD
331
PVQSW
336
KGPGL
341
PRAGC
346
SGLGH
351
PIQLD
356
PNQKT
361
PENSK
366
SLNAV
371
YPRAG
376
SKPPS
381
CPAPG
386
PTGAA
391
SIVPS
396
VPGMA
401
LDLSQ
406
IPTKE
411
LDRFI
416
QDHLK
421
PSPQF
426
QEQVK
431
KAIDI
436
ILRCL
441
HENCV
446
HKASR
451
VSKGG
456
SFGRG
461
TDLRD
466
GCDVE
471
LIIFL
476
NCFTD
481
YKDQG
486
PRRAE
491
ILDEM
496
RAQLE
501
SWWQD
506
QVPSL
511
SLQFP
516
EQNVP
521
EALQF
526
QLVST
531
ALKSW
536
TDVSL
541
LPAFD
546
AVGQL
551
SSGTK
556
PNPQV
561
YSRLL
566
TSGCQ
571
EGEHK
576
ACFAE
581
LRRNF
586
MNIRP
591
VKLKN
596
LILLV
601
KHWYR
606
QVAAQ
611
NKGKG
616
PAPAS
621
LPPAY
626
ALELL
631
TIFAW
636
EQGCR
641
QDCFN
646
MAQGF
651
RTVLG
656
LVQQH
661
QQLCV
666
YWTVN
671
YSTED
676
PAMRM
681
HLLGQ
686
LRKPR
691
PLVLD
696
PADPT
701
WNVGH
706
GSWEL
711
LAQEA
716
AALGM
721
QACFL
726
SRDGT
731
SVQPW
736
DVMPA
741
LLYQT
746
PAGDL
751
DKFIS
756
EFLQP
761
NRQFL
766
AQVNK
771
AVDTI
776
CSFLK
781
ENCFR
786
NSPIK
791
VIKVV
796
KGGSS
801
AKGTA
806
LRGRS
811
DADLV
816
VFLSC
821
FSQFT
826
EQGNK
831
RAEII
836
SEIRA
841
QLEAC
846
QQERQ
851
FEVKF
856
EVSKW
861
ENPRV
866
LSFSL
871
TSQTM
876
LDQSV
881
DFDVL
886
PAFDA
891
LGQLV
896
SGSRP
901
SSQVY
906
VDLIH
911
SYSNA
916
GEYST
921
CFTEL
926
QRDFI
931
ISRPT
936
KLKSL
941
IRLVK
946
HWYQQ
951
CTKIS
956
KGRGS
961
LPPQH
966
GLELL
971
TVYAW
976
EQGGK
981
DSQFN
986
MAEGF
991
RTVLE
996
LVTQY
1001
RQLCI
1006
YWTIN
1011
YNAKD
1016
KTVGD
1021
FLKQQ
1026
LQKPR
1031
PIILD
1036
PADPT
1041
GNLGH
1046
NARWD
1051
LLAKE
1056
AAACT
1061
SALCC
1066
MGRNG
1071
IPIQP
1076
WPVKA
1081
AV
1086
Mutation Information
DNA mutation:
None
Peptide Range:
883 ~ 907
Mut AA position:
895 (13 in Wild Type peptide)
Alignment
Wild Type:
"QSVDFDVLPAFDALGQLVSGSRPSS
||||||||||||.||||||||||||
Mutant:
QSVDFDVLPAFDVLGQLVSGSRPSS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) OAS3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay