Immunogenicity 6157

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PNLIP
Transcript ID
NM_000936
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (465 aa)
MLPLW
1
TLSLL
6
LGAVA
11
GKEVC
16
YERLG
21
CFSDD
26
SPWSG
31
ITERP
36
LHILP
41
WSPKD
46
VNTRF
51
LLYTN
56
ENPNN
61
FQEVA
66
ADSSS
71
ISGSN
76
FKTNR
81
KTRFI
86
IHGFI
91
DKGEE
96
NWLAN
101
VCKNL
106
FKVES
111
VNCIC
116
VDWKG
121
GSRTG
126
YTQAS
131
QNIRI
136
VGAEV
141
AYFVE
146
FLQSA
151
FGYSP
156
SNVHV
161
IGHSL
166
GAHAA
171
GEAGR
176
RTNGT
181
IGRIT
186
GLDPA
191
EPCFQ
196
GTPEL
201
VRLDP
206
SDAKF
211
VDVIH
216
TDGAP
221
IVPNL
226
GFGMS
231
QVVGH
236
LDFFP
241
NGGVE
246
MPGCK
251
KNILS
256
QIVDI
261
DGIWE
266
GTRDF
271
AACNH
276
LRSYK
281
YYTDS
286
IVNPD
291
GFAGF
296
PCASY
301
NVFTA
306
NKCFP
311
CPSGG
316
CPQMG
321
HYADR
326
YPGKT
331
NDVGQ
336
KFYLD
341
TGDAS
346
NFARW
351
RYKVS
356
VTLSG
361
KKVTG
366
HILVS
371
LFGNK
376
GNSKQ
381
YEIFK
386
GTLKP
391
DSTHS
396
NEFDS
401
DVDVG
406
DLQMV
411
KFIWY
416
NNVIN
421
PTLPR
426
VGASK
431
IIVET
436
NVGKQ
441
FNFCS
446
PETVR
451
EEVLL
456
TLTPC
461
Mutation Information
DNA mutation:
None
Peptide Range:
139 ~ 163
Mut AA position:
151 (13 in Wild Type peptide)
Alignment
Wild Type:
"RIVGAEVAYFVEFLQSAFGYSPSNV
||||||||||||.||||||||||||
Mutant:
RIVGAEVAYFVEILQSAFGYSPSNV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PNLIP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay