Immunogenicity 6178

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PDPR
Transcript ID
NM_017990
HLA INFO
B*13:02
TCR INFO

No TCR info found!

T cell Tumor cell B*13:02
sequence
Full length protein sequence (879 aa)
MMFYR
1
LLSIV
6
GRQRA
11
SPGWQ
16
NWSSA
21
RNSTS
26
AAEAR
31
SMALP
36
TQAQV
41
VICGG
46
GITGT
51
SVAYH
56
LSKMG
61
WKDIV
66
LLEQG
71
RLAAG
76
STRFC
81
AGILS
86
TARHL
91
TIEQK
96
MADYS
101
NKLYY
106
QLEQE
111
TGIQT
116
GYTRT
121
GSIFL
126
AQTQD
131
RLISL
136
KRINA
141
GLNVI
146
GIPSE
151
IISPK
156
KVAEL
161
HHLLN
166
VHDLV
171
GAMHV
176
PEDAV
181
VSSAD
186
VALAL
191
ASAAS
196
QNGVQ
201
IYDRT
206
SVLHV
211
MVKKG
216
QVTGV
221
ETDKG
226
QIECQ
231
YFVNC
236
AGQWA
241
YELGL
246
SNEEP
251
VSIPL
256
HACEH
261
FYLLT
266
RPLET
271
PLQSS
276
TPTIV
281
DADGR
286
IYIRN
291
WQGGI
296
LSGGF
301
EKNPK
306
PIFTE
311
GKNQL
316
EIQNL
321
QEDWD
326
HFEPL
331
LSSLL
336
RRMPE
341
LETLE
346
IMKLV
351
NCPET
356
FTPDM
361
RCIMG
366
ESPAV
371
QGYFV
376
LAGMN
381
SAGLS
386
FGGGA
391
GKYLA
396
EWMVH
401
GYPSE
406
NVWEL
411
DLKRF
416
GALQS
421
SRTFL
426
RHRVM
431
EVMPL
436
MYDLK
441
VPRWD
446
FQTGR
451
QLRTS
456
PLYDR
461
LDAQG
466
ARWME
471
KHGFE
476
RPKYF
481
VPPDK
486
DLLAL
491
EQSKT
496
FYKPD
501
WFDIV
506
ESEVK
511
CCKEA
516
VCVID
521
MSSFT
526
KFEIT
531
STGDQ
536
ALEVL
541
QYLFS
546
NDLDV
551
PVGHI
556
VHTGM
561
LNEGG
566
GYEND
571
CSIAR
576
LNKRS
581
FFMIS
586
PTDQQ
591
VHCWA
596
WLKKH
601
MPKDS
606
NLLLE
611
DVTWK
616
YTALN
621
LIGPR
626
AVDVL
631
SELSY
636
APMTP
641
DHFPS
646
LFCKE
651
MSVGY
656
ANGIR
661
VMSMT
666
HTGEP
671
GFMLY
676
IPIEY
681
ALHVY
686
NEVMS
691
VGQKY
696
GIRNA
701
GYYAL
706
RSLRI
711
EKFFA
716
FWGQD
721
INNLT
726
TPLEC
731
GRESR
736
VKLEK
741
GMDFI
746
GRDAL
751
LQQKQ
756
NGVYK
761
RLTMF
766
ILDDH
771
DSDLD
776
LWPWW
781
GEPIY
786
RNGQY
791
VGKTT
796
SSAYS
801
YSLER
806
HVCLG
811
FVHNF
816
SEDTG
821
EEQVV
826
TADFI
831
NRGEY
836
EIDIA
841
GYRFQ
846
AKAKL
851
YPVAS
856
LFTQK
861
RRKDD
866
MELSD
871
LHGK
876
Mutation Information
DNA mutation:
None
Peptide Range:
282 ~ 306
Mut AA position:
294 (13 in Wild Type peptide)
Alignment
Wild Type:
"PTIVDADGRIYIRNWQGGILSGGFE
||||||||||||.||||||||||||
Mutant:
PTIVDADGRIYIQNWQGGILSGGFE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PDPR

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay