Immunogenicity 6232
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
UNC13C
Transcript ID
NM_001080534
HLA INFO
A*30:02
TCR INFO
No TCR info found!
Full length protein sequence (2214 aa)
MVANF
1
FKSLI
6
LPYIH
11
KLCKG
16
MFTKK
21
LGNTN
26
KNKEY
31
RQQKK
36
DQDFP
41
TAGQT
46
KSPKF
51
SYTFK
56
STVKK
61
IAKCS
66
STHNL
71
STEED
76
EASKE
81
FSLSP
86
TFSYR
91
VAIAN
96
GLQKN
101
AKVTN
106
SDNED
111
LLQEL
116
SSIES
121
SYSES
126
LNELR
131
SSTEN
136
QAQST
141
HTMPV
146
RRNRK
151
SSSSL
156
APSEG
161
SSDGE
166
RTLHG
171
LKLGA
176
LRKLR
181
KWKKS
186
QECVS
191
SDSEL
196
STMKK
201
SWGIR
206
SKSLD
211
RTVRN
216
PKTNA
221
LEPGF
226
SSSGC
231
ISQTH
236
DVMEM
241
IFKEL
246
QGISQ
251
IETEL
256
SELRG
261
HVNAL
266
KHSID
271
EISSS
276
VEVVQ
281
SEIEQ
286
LRTGF
291
VQSRR
296
ETRDI
301
HDYIK
306
HLGHM
311
GSKAS
316
LRFLN
321
VTEER
326
FEYVE
331
SVVYQ
336
ILIDK
341
MGFSD
346
APNAI
351
KIEFA
356
QRIGH
361
QRDCP
366
NAKPR
371
PILVY
376
FETPQ
381
QRDSV
386
LKKSY
391
KLKGT
396
GIGIS
401
TDILT
406
HDIRE
411
RKEKG
416
IPSSQ
421
TYESM
426
AIKLS
431
TPEPK
436
IKKNN
441
WQSPD
446
DSDED
451
LESDL
456
NRNSY
461
AVLSK
466
SELLT
471
KGSTS
476
KPSSK
481
SHSAR
486
SKNKT
491
ANSSR
496
ISNKS
501
DYDKI
506
SSQLP
511
ESDIL
516
EKQTT
521
THYAD
526
ATPLW
531
HSQSD
536
FFTAK
541
LSRSE
546
SDFSK
551
LCQSY
556
SEDFS
561
ENQFF
566
TRTNG
571
SSLLS
576
SSDRE
581
LWQRK
586
QEGTA
591
TLYDS
596
PKDQH
601
LNGGV
606
QGIQG
611
QTETE
616
NTETV
621
DSGMS
626
NGMVC
631
ASGDR
636
SHYSD
641
SQLSL
646
HEDLS
651
PWKEW
656
NQGAD
661
LGLDS
666
STQEG
671
FDYET
676
NSLFD
681
QQLDV
686
YNKDL
691
EYLGK
696
CHSDL
701
QDDSE
706
SYDLT
711
QDDNS
716
SPCPG
721
LDNEP
726
QGQWV
731
GQYDS
736
YQGAN
741
SNELY
746
QNQNQ
751
LSMMY
756
RSQSE
761
LQSDD
766
SEDAP
771
PKSWH
776
SRLSI
781
DLSDK
786
TFSFP
791
KFGST
796
LQRAK
801
SALEV
806
VWNKS
811
TQSLS
816
GYEDS
821
GSSLM
826
GRFRT
831
LSQST
836
ANESS
841
TTLDS
846
DVYTE
851
PYYYK
856
AEDEE
861
DYTEP
866
VADNE
871
TDYVE
876
VMEQV
881
LAKLE
886
NRTSI
891
TETDE
896
QMQAY
901
DHLSY
906
ETPYE
911
TPQDE
916
GYDGP
921
ADDMV
926
SEEGL
931
EPLNE
936
TSAEM
941
EIRED
946
ENQNI
951
PEQPV
956
EITKP
961
KRIRP
966
SFKEA
971
ALRAY
976
KKQMA
981
ELEEK
986
ILAGD
991
SSSVD
996
EKARI
1001
VSGND
1006
LDASK
1011
FSALQ
1016
VCGGA
1021
GGGLY
1026
GIDSM
1031
PDLRR
1036
KKTLP
1041
IVRDV
1046
AMTLA
1051
ARKSG
1056
LSLAM
1061
VIRTS
1066
LNNEE
1071
LKMHV
1076
FKKTL
1081
QALIY
1086
PMSST
1091
IPHNF
1096
EVWTA
1101
TTPTY
1106
CYECE
1111
GLLWG
1116
IARQG
1121
MKCLE
1126
CGVKC
1131
HEKCQ
1136
DLLNA
1141
DCLQR
1146
AAEKS
1151
SKHGA
1156
EDKTQ
1161
TIITA
1166
MKERM
1171
KIREK
1176
NRPEV
1181
FEVIQ
1186
EMFQI
1191
SKEDF
1196
VQFTK
1201
AAKQS
1206
VLDGT
1211
SKWSA
1216
KITIT
1221
VVSAQ
1226
GLQAK
1231
DKTGS
1236
SDPYV
1241
TVQVG
1246
KNKRR
1251
TKTIF
1256
GNLNP
1261
VWDEK
1266
FYFEC
1271
HNSTD
1276
RIKVR
1281
VWDED
1286
DDIKS
1291
RVKQH
1296
FKKES
1301
DDFLG
1306
QTIVE
1311
VRTLS
1316
GEMDV
1321
WYNLE
1326
KRTDK
1331
SAVSG
1336
AIRLK
1341
INVEI
1346
KGEEK
1351
VAPYH
1356
IQYTC
1361
LHENL
1366
FHYLT
1371
EVKSN
1376
GGVKI
1381
PEVKG
1386
DEAWK
1391
VFFDD
1396
ASQEI
1401
VDEFA
1406
MRYGI
1411
ESIYQ
1416
AMTHF
1421
SCLSS
1426
KYMCP
1431
GVPAV
1436
MSTLL
1441
ANINA
1446
FYAHT
1451
TVSTN
1456
IQVSA
1461
SDRFA
1466
ATNFG
1471
REKFI
1476
KLLDQ
1481
LHNSL
1486
RIDLS
1491
KYREN
1496
FPASN
1501
TERLQ
1506
DLKST
1511
VDLLT
1516
SITFF
1521
RMKVL
1526
ELQSP
1531
PKASM
1536
VVKDC
1541
VRACL
1546
DSTYK
1551
YIFDN
1556
CHELY
1561
SQLTD
1566
PSKKQ
1571
DIPRE
1576
DQGPT
1581
TKNLD
1586
FWPQL
1591
ITLMV
1596
TIIDE
1601
DKTAY
1606
TPVLN
1611
QFPQE
1616
LNMGK
1621
ISAEI
1626
MWTLF
1631
ALDMK
1636
YALEE
1641
HENQR
1646
LCKST
1651
DYMNL
1656
HFKVK
1661
WFYNE
1666
YVREL
1671
PAFKD
1676
AVPEY
1681
SLWFE
1686
PFVMQ
1691
WLDEN
1696
EDVSM
1701
EFLHG
1706
ALGRD
1711
KKDGF
1716
QQTSE
1721
HALFS
1726
CSVVD
1731
VFAQL
1736
NQSFE
1741
IIKKL
1746
ECPNP
1751
EALSH
1756
LMRRF
1761
AKTIN
1766
KVLLQ
1771
YAAIV
1776
SSDFS
1781
SHCDK
1786
ENVPC
1791
ILMNN
1796
IQQLR
1801
VQLEK
1806
MFESM
1811
GGKEL
1816
DSEAS
1821
TILKE
1826
LQVKL
1831
SGVLD
1836
ELSVT
1841
YGESF
1846
QVIIE
1851
ECIKQ
1856
MSFEL
1861
NQMRA
1866
NGNTT
1871
SNKNS
1876
AAMDA
1881
EIVLR
1886
SLMDF
1891
LDKTL
1896
SLSAK
1901
ICEKT
1906
VLKRV
1911
LKELW
1916
KLVLN
1921
KIEKQ
1926
IVLPP
1931
LTDQT
1936
GPQMI
1941
FIAAK
1946
DLGQL
1951
SKLKE
1956
HMIRE
1961
DARGL
1966
TPRQC
1971
AIMEV
1976
VLATI
1981
KQYFH
1986
AGGNG
1991
LKKNF
1996
LEKSP
2001
DLQSL
2006
RYALS
2011
LYTQT
2016
TDALI
2021
KKFID
2026
TQTSQ
2031
SRSSK
2036
DAVGQ
2041
ISVHV
2046
DITAT
2051
PGTGD
2056
HKVTV
2061
KVIAI
2066
NDLNW
2071
QTTAM
2076
FRPFV
2081
EVCIL
2086
GPNLG
2091
DKKRK
2096
QGTKT
2101
KSNTW
2106
SPKYN
2111
ETFQF
2116
ILGKE
2121
NRPGA
2126
YELHL
2131
SVKDY
2136
CFARE
2141
DRIIG
2146
MTVIQ
2151
LQNIA
2156
EKGSY
2161
GAWYP
2166
LLKNI
2171
SMDET
2176
GLTIL
2181
RILSQ
2186
RTSDD
2191
VAKEF
2196
VRLKS
2201
ETRST
2206
EESA
2211
Mutation Information
DNA mutation:
None
Peptide Range:
307 ~ 331
Mut AA position:
319 (13 in Wild Type peptide)
Alignment
Wild Type:
"DYIKHLGHMGSKASLRFLNVTEERF
||||||||||||.||||||||||||
Mutant:
DYIKHLGHMGSKESLRFLNVTEERF"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) UNC13C
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay