Immunogenicity 6239
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
TSHZ3
Transcript ID
NM_020856
HLA INFO
C*16:01
TCR INFO
No TCR info found!
Full length protein sequence (1081 aa)
MPRRK
1
QQAPR
6
RAAAY
11
VSEEL
16
KAAAL
21
VDEGL
26
DPEEH
31
TADGE
36
PSAKY
41
MCPEK
46
ELARA
51
CPSYQ
56
NSPAA
61
EFSCH
66
EMDSE
71
SHISE
76
TSDRM
81
ADFES
86
GSIKN
91
EEETK
96
EVTVP
101
LEDTT
106
VSDSL
111
EQMKA
116
VYNNF
121
LSNSY
126
WSNLN
131
LNLHQ
136
PSSEK
141
NNGSS
146
SSSSS
151
SSSSC
156
GSGSF
161
DWHQS
166
AMAKT
171
LQQVS
176
QSRML
181
PEPSL
186
FSTVQ
191
LYRQS
196
SKLYG
201
SIFTG
206
ASKFR
211
CKDCS
216
AAYDT
221
LVELT
226
VHMNE
231
TGHYR
236
DDNHE
241
TDNNN
246
PKRWS
251
KPRKR
256
SLLEM
261
EGKED
266
AQKVL
271
KCMYC
276
GHSFE
281
SLQDL
286
SVHMI
291
KTKHY
296
QKVPL
301
KEPVT
306
PVAAK
311
IIPAT
316
RKKAS
321
LELEL
326
PSSPD
331
STGGT
336
PKATI
341
SDTND
346
ALQKN
351
SNPYI
356
TPNNR
361
YGHQN
366
GASYA
371
WHFEA
376
RKSQI
381
LKCME
386
CGSSH
391
DTLQE
396
LTAHM
401
MVTGH
406
FIKVT
411
NSAMK
416
KGKPI
421
VETPV
426
TPTIT
431
TLLDE
436
KVQSV
441
PLAAT
446
TFTSP
451
SNTPA
456
SISPK
461
LNVEV
466
KKEVD
471
KEKAV
476
TDEKP
481
KQKDK
486
PGEEE
491
EKCDI
496
SSKYH
501
YLTEN
506
DLEES
511
PKGGL
516
DILKS
521
LENTV
526
TSAIN
531
KAQNG
536
TPSWG
541
GYPSI
546
HAAYQ
551
LPNMM
556
KLSLG
561
SSGKS
566
TPLKP
571
MFGNS
576
EIVSP
581
TKNQT
586
LVSPP
591
SSQTS
596
PMPKT
601
NFHAM
606
EELVK
611
KVTEK
616
VAKVE
621
EKMKE
626
PDGKL
631
SPPKR
636
ATPSP
641
CSSEV
646
GEPIK
651
MEASS
656
DGGFR
661
SQENS
666
PSPPR
671
DGCKD
676
GSPLA
681
EPVEN
686
GKELV
691
KPLAS
696
SLSGS
701
TAIIT
706
DHPPE
711
QPFVN
716
PLSAL
721
QSVMN
726
IHLGK
731
AAKPS
736
LPALD
741
PMSML
746
FKMSN
751
SLAEK
756
AAVAT
761
PPPLQ
766
SKKAD
771
HLDRY
776
FYHVN
781
NDQPI
786
DLTKG
791
KSDKG
796
CSLGS
801
VLLSP
806
TSTAP
811
ATSSS
816
TVTTA
821
KTSAV
826
VSFMS
831
NSPLR
836
ENALS
841
DISDM
846
LKNLT
851
ESHTS
856
KSSTP
861
SSISE
866
KSDID
871
GATLE
876
EAEES
881
TPAQK
886
RKGRQ
891
SNWNP
896
QHLLI
901
LQAQF
906
AASLR
911
QTSEG
916
KYIMS
921
DLSPQ
926
ERMHI
931
SRFTG
936
LSMTT
941
ISHWL
946
ANVKY
951
QLRRT
956
GGTKF
961
LKNLD
966
TGHPV
971
FFCND
976
CASQI
981
RTPST
986
YISHL
991
ESHLG
996
FRLRD
1001
LSKLS
1006
TEQIN
1011
SQIAQ
1016
TKSPS
1021
EKMVT
1026
SSPEE
1031
DLGTS
1036
YQCKL
1041
CNRTF
1046
ASKHA
1051
VKLHL
1056
SKTHG
1061
KSPED
1066
HLLYV
1071
SELEK
1076
Q
1081
Mutation Information
DNA mutation:
None
Peptide Range:
235 ~ 259
Mut AA position:
247 (13 in Wild Type peptide)
Alignment
Wild Type:
"ETGHYRDDNHETDNNNPKRWSKPRK
||||||||||||.||||||||||||
Mutant:
ETGHYRDDNHETNNNNPKRWSKPRK"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) TSHZ3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay