Immunogenicity 6309

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HSD17B1
Transcript ID
NM_000413
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (328 aa)
MARTV
1
VLITG
6
CSSGI
11
GLHLA
16
VRLAS
21
DPSQS
26
FKVYA
31
TLRDL
36
KTQGR
41
LWEAA
46
RALAC
51
PPGSL
56
ETLQL
61
DVRDS
66
KSVAA
71
ARERV
76
TEGRV
81
DVLVC
86
NAGLG
91
LLGPL
96
EALGE
101
DAVAS
106
VLDVN
111
VVGTV
116
RMLQA
121
FLPDM
126
KRRGS
131
GRVLV
136
TGSVG
141
GLMGL
146
PFNDV
151
YCASK
156
FALEG
161
LCESL
166
AVLLL
171
PFGVH
176
LSLIE
181
CGPVH
186
TAFME
191
KVLGS
196
PEEVL
201
DRTDI
206
HTFHR
211
FYQYL
216
AHSKQ
221
VFREA
226
AQNPE
231
EVAEV
236
FLTAL
241
RAPKP
246
TLRYF
251
TTERF
256
LPLLR
261
MRLDD
266
PSGSN
271
YVTAM
276
HREVF
281
GDVPA
286
KAEAG
291
AEAGG
296
GAGPG
301
AEDEA
306
GRGAV
311
GDPEL
316
GDPPA
321
APQ
326
Mutation Information
DNA mutation:
None
Peptide Range:
132 ~ 156
Mut AA position:
144 (13 in Wild Type peptide)
Alignment
Wild Type:
"RRGSGRVLVTGSVGGLMGLPFNDVY
||||||||||||.||||||||||||
Mutant:
RRGSGRVLVTGSLGGLMGLPFNDVY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HSD17B1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay