Immunogenicity 6314
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
NLRP3
Transcript ID
NM_001079821
HLA INFO
DRB*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1036 aa)
MKMAS
1
TRCKL
6
ARYLE
11
DLEDV
16
DLKKF
21
KMHLE
26
DYPPQ
31
KGCIP
36
LPRGQ
41
TEKAD
46
HVDLA
51
TLMID
56
FNGEE
61
KAWAM
66
AVWIF
71
AAINR
76
RDLYE
81
KAKRD
86
EPKWG
91
SDNAR
96
VSNPT
101
VICQE
106
DSIEE
111
EWMGL
116
LEYLS
121
RISIC
126
KMKKD
131
YRKKY
136
RKYVR
141
SRFQC
146
IEDRN
151
ARLGE
156
SVSLN
161
KRYTR
166
LRLIK
171
EHRSQ
176
QEREQ
181
ELLAI
186
GKTKT
191
CESPV
196
SPIKM
201
ELLFD
206
PDDEH
211
SEPVH
216
TVVFQ
221
GAAGI
226
GKTIL
231
ARKMM
236
LDWAS
241
GTLYQ
246
DRFDY
251
LFYIH
256
CREVS
261
LVTQR
266
SLGDL
271
IMSCC
276
PDPNP
281
PIHKI
286
VRKPS
291
RILFL
296
MDGFD
301
ELQGA
306
FDEHI
311
GPLCT
316
DWQKA
321
ERGDI
326
LLSSL
331
IRKKL
336
LPEAS
341
LLITT
346
RPVAL
351
EKLQH
356
LLDHP
361
RHVEI
366
LGFSE
371
AKRKE
376
YFFKY
381
FSDEA
386
QARAA
391
FSLIQ
396
ENEVL
401
FTMCF
406
IPLVC
411
WIVCT
416
GLKQQ
421
MESGK
426
SLAQT
431
SKTTT
436
AVYVF
441
FLSSL
446
LQPRG
451
GSQEH
456
GLCAH
461
LWGLC
466
SLAAD
471
GIWNQ
476
KILFE
481
ESDLR
486
NHGLQ
491
KADVS
496
AFLRM
501
NLFQK
506
EVDCE
511
KFYSF
516
IHMTF
521
QEFFA
526
AMYYL
531
LEEEK
536
EGRTN
541
VPGSR
546
LKLPS
551
RDVTV
556
LLENY
561
GKFEK
566
GYLIF
571
VVRFL
576
FGLVN
581
QERTS
586
YLEKK
591
LSCKI
596
SQQIR
601
LELLK
606
WIEVK
611
AKAKK
616
LQIQP
621
SQLEL
626
FYCLY
631
EMQEE
636
DFVQR
641
AMDYF
646
PKIEI
651
NLSTR
656
MDHMV
661
SSFCI
666
ENCHR
671
VESLS
676
LGFLH
681
NMPKE
686
EEEEE
691
KEGRH
696
LDMVQ
701
CVLPS
706
SSHAA
711
CSHGL
716
VNSHL
721
TSSFC
726
RGLFS
731
VLSTS
736
QSLTE
741
LDLSD
746
NSLGD
751
PGMRV
756
LCETL
761
QHPGC
766
NIRRL
771
WLGRC
776
GLSHE
781
CCFDI
786
SLVLS
791
SNQKL
796
VELDL
801
SDNAL
806
GDFGI
811
RLLCV
816
GLKHL
821
LCNLK
826
KLWLV
831
SCCLT
836
SACCQ
841
DLASV
846
LSTSH
851
SLTRL
856
YVGEN
861
ALGDS
866
GVAIL
871
CEKAK
876
NPQCN
881
LQKLG
886
LVNSG
891
LTSVC
896
CSALS
901
SVLST
906
NQNLT
911
HLYLR
916
GNTLG
921
DKGIK
926
LLCEG
931
LLHPD
936
CKLQV
941
LELDN
946
CNLTS
951
HCCWD
956
LSTLL
961
TSSQS
966
LRKLS
971
LGNND
976
LGDLG
981
VMMFC
986
EVLKQ
991
QSCLL
996
QNLGL
1001
SEMYF
1006
NYETK
1011
SALET
1016
LQEEK
1021
PELTV
1026
VFEPS
1031
W
1036
Mutation Information
DNA mutation:
None
Peptide Range:
198 ~ 222
Mut AA position:
210 (13 in Wild Type peptide)
Alignment
Wild Type:
"SPVSPIKMELLFDPDDEHSEPVHTV
||||||||||||.||||||||||||
Mutant:
SPVSPIKMELLFVPDDEHSEPVHTV"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) NLRP3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay