Immunogenicity 6330

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MUC1
Transcript ID
NM_001204286
HLA INFO
C*07:02
TCR INFO

No TCR info found!

T cell Tumor cell C*07:02
sequence
Full length protein sequence (484 aa)
MTPGT
1
QSPFF
6
LLLLL
11
TVLTA
16
TTAPK
21
PATVV
26
TGSGH
31
ASSTP
36
GGEKE
41
TSATQ
46
RSSVP
51
SSTEK
56
NAVSM
61
TSSVL
66
SSHSP
71
GSGSS
76
TTQGQ
81
DVTLA
86
PATEP
91
ASGSA
96
ATWGQ
101
DVTSV
106
PVTRP
111
ALGST
116
TPPAH
121
DVTSA
126
PDNKP
131
APGST
136
APPAH
141
GVTSA
146
PDTRP
151
APGST
156
APPAH
161
GVTSA
166
PDNRP
171
ALGST
176
APPVH
181
NVTSA
186
SGSAS
191
GSAST
196
LVHNG
201
TSARA
206
TTTPA
211
SKSTP
216
FSIPS
221
HHSDT
226
PTTLA
231
SHSTK
236
TDASS
241
THHST
246
VPPLT
251
SSNHS
256
TSPQL
261
STGVS
266
FFFLS
271
FHISN
276
LQFNS
281
SLEDP
286
STDYY
291
QELQR
296
DISEM
301
FLQIY
306
KQGGF
311
LGLSN
316
IKFRP
321
GSVVV
326
QLTLA
331
FREGT
336
INVHD
341
VETQF
346
NQYKT
351
EAASR
356
YNLTI
361
SDVSV
366
SDVPF
371
PFSAQ
376
SGAGV
381
PGWGI
386
ALLVL
391
VCVLV
396
ALAIV
401
YLIAL
406
AVCQC
411
RRKNY
416
GQLDI
421
FPARD
426
TYHPM
431
SEYPT
436
YHTHG
441
RYVPP
446
SSTDR
451
SPYEK
456
VSAGN
461
GGSSL
466
SYTNP
471
AVAAT
476
SANL
481
Mutation Information
DNA mutation:
None
Peptide Range:
109 ~ 133
Mut AA position:
121 (13 in Wild Type peptide)
Alignment
Wild Type:
"SVPVTRPALGSTTPPAHDVTSAPDN
||||||||||||.||||||||||||
Mutant:
SVPVTRPALGSTPPPAHDVTSAPDN"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MUC1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay