Immunogenicity 6342

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
RHPN2
Transcript ID
NM_033103
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (686 aa)
MTDAL
1
LPAAP
6
QPLEK
11
ENDGY
16
FRKGC
21
NPLAQ
26
TGRSK
31
LQNQR
36
AALNQ
41
QILKA
46
VRMRT
51
GAENL
56
LKVAT
61
NSKVR
66
EQVRL
71
ELSFV
76
NSDLQ
81
MLKEE
86
LEGLN
91
ISVGV
96
YQNTE
101
EAFTI
106
PLIPL
111
GLKET
116
KDVDF
121
AVVLK
126
DFILE
131
HYSED
136
GYLYE
141
DEIAD
146
LMDLR
151
QACRT
156
PSRDE
161
AGVEL
166
LMTYF
171
IQLGF
176
VESRF
181
FPPTR
186
QMGLL
191
FTWYD
196
SLTGV
201
PVSQQ
206
NLLLE
211
KASVL
216
FNTGA
221
LYTQI
226
GTRCD
231
RQTQA
236
GLESA
241
IDAFQ
246
RAAGV
251
LNYLK
256
DTFTH
261
TPSYD
266
MSPAM
271
LSVLV
276
KMMLA
281
QAQES
286
VFEKI
291
SLPGI
296
RNEFF
301
MLVKV
306
AQEAA
311
KVGEV
316
YQQLH
321
AAMSQ
326
APVKE
331
NIPYS
336
WASLA
341
CVKAH
346
HYAAL
351
AHYFT
356
AILLI
361
DHQVK
366
PGTDL
371
DHQEK
376
CLSQL
381
YDHMP
386
EGLTP
391
LATLK
396
NDQQR
401
RQLGK
406
SHLRR
411
AMAHH
416
EESVR
421
EASLC
426
KKLRS
431
IEVLQ
436
KVLCA
441
AQERS
446
RLTYA
451
QHQEE
456
DDLLN
461
LIDAP
466
SVVAK
471
TEQEV
476
DIILP
481
QFSKL
486
TVTDF
491
FQKLG
496
PLSVF
501
SANKR
506
WTPPR
511
SIRFT
516
AEEGD
521
LGFTL
526
RGNAP
531
VQVHF
536
LDPYC
541
SASVA
546
GAREG
551
DYIVS
556
IQLVD
561
CKWLT
566
LSEVM
571
KLLKS
576
FGEDE
581
IEMKV
586
VSLLD
591
STSSM
596
HNKSA
601
TYSVG
606
MQKTY
611
SMICL
616
AIDDD
621
DKTDK
626
TKKIS
631
KKLSF
636
LSWGT
641
NKNRQ
646
KSAST
651
LCLPS
656
VGAAR
661
PQVKK
666
KLPSP
671
FSLLN
676
SDSSW
681
Y
686
Mutation Information
DNA mutation:
None
Peptide Range:
372 ~ 396
Mut AA position:
384 (13 in Wild Type peptide)
Alignment
Wild Type:
"GTDLDHQEKCLSQLYDHMPEGLTPL
||||||||||||.||||||||||||
Mutant:
GTDLDHQEKCLSRLYDHMPEGLTPL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RHPN2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay